| Transcript ID | HUVEC |
|---|---|
| ENST00000381318 | 0.803±0.15 |
Transcript Info |
||||||
| Description: | intersectin 1 (SH3 domain protein) | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
|
ENST00000381318 |
ITSN1-001 |
ENSG00000205726 |
9606 | + |
21:33642458-33899861 |
protein_coding |
Expression Patterns
|
Conserved Regions |
|---|
| Not located within a conserved region. |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0005085 | NAS | guanyl-nucleotide exchange factor activity |
| GO:0005089 | IEA | Rho guanyl-nucleotide exchange factor activity |
| GO:0005509 | IEA:NAS | calcium ion binding |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005829 | TAS | cytosol |
| GO:0005886 | IDA | plasma membrane |
| GO:0005905 | IDA | coated pit |
| GO:0007264 | TAS | small GTPase mediated signal transduction |
| GO:0019209 | IEA | kinase activator activity |
| GO:0030027 | IEA | lamellipodium |
| GO:0030054 | IEA | cell junction |
| GO:0030139 | IEA | endocytic vesicle |
| GO:0032321 | IEA | positive regulation of Rho GTPase activity |
| GO:0032947 | IDA | protein complex scaffold |
| GO:0035023 | IEA | regulation of Rho protein signal transduction |
| GO:0042327 | IEA | positive regulation of phosphorylation |
| GO:0043005 | IEA | neuron projection |
| GO:0043065 | TAS | positive regulation of apoptotic process |
| GO:0043524 | IEA | negative regulation of neuron apoptotic process |
| GO:0043547 | NAS | positive regulation of GTPase activity |
| GO:0045202 | IEA | synapse |
| GO:0048011 | TAS | neurotrophin TRK receptor signaling pathway |
| GO:0048488 | TAS | synaptic vesicle endocytosis |
| GO:0051056 | TAS | regulation of small GTPase mediated signal transduction |
| GO:0051897 | IEA | positive regulation of protein kinase B signaling |
| GO:0070064 | IPI | proline-rich region binding |
| GO:0097190 | TAS | apoptotic signaling pathway |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSMUST00000064797
|
Itsn1-008 | protein_coding | Mus_musculus | 0 | 6397 |
|
ENSMUST00000114002
|
Itsn1-001 | protein_coding | Mus_musculus | 0 | 6300 |
|
ENSMUST00000113999
|
Itsn1-006 | protein_coding | Mus_musculus | 0 | 4375 |
|
ENSMUST00000056482
|
Itsn1-003 | protein_coding | Mus_musculus | 0 | 4263 |
|
ENSMUST00000114001
|
Itsn1-004 | protein_coding | Mus_musculus | 0 | 3463 |
|
ENSMUST00000113996
|
Itsn1-010 | protein_coding | Mus_musculus | 0 | 3408 |
|
ENSMUST00000113993
|
Itsn1-005 | protein_coding | Mus_musculus | 0 | 3338 |
|
ENSMUST00000095909
|
Itsn1-002 | protein_coding | Mus_musculus | 0 | 2263 |
|
ENSMUST00000135057
|
Itsn1-009 | protein_coding | Mus_musculus | 0 | 797 |
|
ENSMUST00000125052
|
Itsn1-016 | protein_coding | Mus_musculus | 0 | 765 |
|
ENSMUST00000151044
|
Itsn1-024 | processed_transcript | Mus_musculus | 0 | 676 |
|
ENSMUST00000131983
|
Itsn1-021 | retained_intron | Mus_musculus | 0 | 531 |
|
ENSMUST00000141073
|
Itsn1-028 | processed_transcript | Mus_musculus | 0 | 525 |
|
ENSMUST00000138117
|
Itsn1-015 | retained_intron | Mus_musculus | 0 | 497 |
|
ENSMUST00000141625
|
Itsn1-018 | protein_coding | Mus_musculus | 0 | 483 |
|
ENSMUST00000143023
|
Itsn1-027 | protein_coding | Mus_musculus | 0 | 477 |
|
ENSMUST00000124094
|
Itsn1-022 | processed_transcript | Mus_musculus | 0 | 455 |
|
ENSMUST00000131739
|
Itsn1-017 | nonsense_mediated_decay | Mus_musculus | 0 | 364 |
|
ENSMUST00000133389
|
Itsn1-007 | processed_transcript | Mus_musculus | 0 | 357 |
|
ENSMUST00000156841
|
Itsn1-023 | retained_intron | Mus_musculus | 0 | 224 |
|
ENSMUST00000126374
|
Itsn1-013 | nonsense_mediated_decay | Mus_musculus | 0 | 204 |
|
ENSMUST00000144101
|
Itsn1-025 | retained_intron | Mus_musculus | 0 | 196 |
|
ENSMUST00000173269
|
Neu1-002 | retained_intron | Mus_musculus | 0.000007 | 60 |
|
ENSMUST00000034431
|
Tmem170-201 | protein_coding | Mus_musculus | 0.00009 | 57 |