ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: msh homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000382723 MSX1-001 ENSG00000163132 9606 + 4:4859666-4863936 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000382723
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000382723 8.551±2.63 1.147±0.75 3.309±0.00 2.381±1.76

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000902 IDA cell morphogenesis
GO:0000977 IEA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000982 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0001227 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 IEA RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001701 IEA in utero embryonic development
GO:0001837 IEA epithelial to mesenchymal transition
GO:0002039 IPI p53 binding
GO:0003007 IEA heart morphogenesis
GO:0003198 IEA epithelial to mesenchymal transition involved in endocardial cushion formation
GO:0003677 IEA DNA binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0007507 IEA heart development
GO:0007517 IEA muscle organ development
GO:0008285 IEA negative regulation of cell proliferation
GO:0009952 IEA anterior/posterior pattern specification
GO:0010463 IEA mesenchymal cell proliferation
GO:0021983 IEA pituitary gland development
GO:0023019 IEA signal transduction involved in regulation of gene expression
GO:0030308 IDA negative regulation of cell growth
GO:0030326 IEA embryonic limb morphogenesis
GO:0030509 IEA BMP signaling pathway
GO:0030513 IEA positive regulation of BMP signaling pathway
GO:0030900 IEA forebrain development
GO:0030901 IEA midbrain development
GO:0034504 IDA protein localization to nucleus
GO:0035115 IEA embryonic forelimb morphogenesis
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0035880 IMP embryonic nail plate morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042476 IEA odontogenesis
GO:0042481 IEA regulation of odontogenesis
GO:0042733 IEA embryonic digit morphogenesis
GO:0043066 IEA negative regulation of apoptotic process
GO:0043392 IEA negative regulation of DNA binding
GO:0043517 IC positive regulation of DNA damage response, signal transduction by p53 class mediator
GO:0043565 IEA sequence-specific DNA binding
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048863 IEA stem cell differentiation
GO:0050821 IDA protein stabilization
GO:0051154 IEA negative regulation of striated muscle cell differentiation
GO:0051216 IEA cartilage development
GO:0060021 IEA palate development
GO:0060325 IMP face morphogenesis
GO:0060349 IEA bone morphogenesis
GO:0060536 IEA cartilage morphogenesis
GO:0061180 IEA mammary gland epithelium development
GO:0061312 IEA BMP signaling pathway involved in heart development
GO:0071316 IEA cellular response to nicotine
GO:0090427 IEA activation of meiosis
GO:1902255 IDA positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding
GO:2001055 IEA positive regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000063116 Msx1-001 protein_coding Mus_musculus 0 1188
ENSMUST00000183013 Msx1-003 retained_intron Mus_musculus 0 627
ENSDART00000002232 msxe-201 protein_coding Danio_rerio 0 255
ENSMUST00000188606 Msx2-002 retained_intron Mus_musculus 0.0000008 60
ENSMUST00000021922 Msx2-001 protein_coding Mus_musculus 0.0000008 60

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