ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: intersectin 1 (SH3 domain protein)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399349 ITSN1-003 ENSG00000205726 9606 + 21:33642498-33838496 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000399349
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000399349 1.756±0.00 5.070±2.40 8.155±0.00 7.409±0.00 5.746±3.26

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 NAS guanyl-nucleotide exchange factor activity
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005509 IEA:NAS calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005829 TAS cytosol
GO:0005886 IDA plasma membrane
GO:0005905 IDA coated pit
GO:0007264 TAS small GTPase mediated signal transduction
GO:0030054 IEA cell junction
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032947 IDA protein complex scaffold
GO:0043005 IEA neuron projection
GO:0043065 TAS positive regulation of apoptotic process
GO:0043547 NAS positive regulation of GTPase activity
GO:0045202 IEA synapse
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048488 TAS synaptic vesicle endocytosis
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070064 IPI proline-rich region binding
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000113996 Itsn1-010 protein_coding Mus_musculus 0 4961
ENSMUST00000113993 Itsn1-005 protein_coding Mus_musculus 0 4143
ENSMUST00000056482 Itsn1-003 protein_coding Mus_musculus 0 3474
ENSMUST00000114002 Itsn1-001 protein_coding Mus_musculus 0 3474
ENSMUST00000064797 Itsn1-008 protein_coding Mus_musculus 0 3406
ENSMUST00000113999 Itsn1-006 protein_coding Mus_musculus 0 3406
ENSMUST00000114001 Itsn1-004 protein_coding Mus_musculus 0 2680
ENSMUST00000095909 Itsn1-002 protein_coding Mus_musculus 0 2257
ENSMUST00000138117 Itsn1-015 retained_intron Mus_musculus 0 1487
ENSMUST00000135057 Itsn1-009 protein_coding Mus_musculus 0 797
ENSMUST00000151044 Itsn1-024 processed_transcript Mus_musculus 0 676
ENSMUST00000131983 Itsn1-021 retained_intron Mus_musculus 0 531
ENSMUST00000124094 Itsn1-022 processed_transcript Mus_musculus 0 455
ENSMUST00000133389 Itsn1-007 processed_transcript Mus_musculus 0 357
ENSMUST00000156841 Itsn1-023 retained_intron Mus_musculus 0 224
ENSMUST00000126374 Itsn1-013 nonsense_mediated_decay Mus_musculus 0 204
ENSMUST00000144101 Itsn1-025 retained_intron Mus_musculus 0 196

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