ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: calcium channel, voltage-dependent, L type, alpha 1C subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000399603 CACNA1C-011 ENSG00000151067 9606 + 12:2053563-2692159 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000399603
Transcript ID HAoEC HUVEC
ENST00000399603 0.014±0.01 0.004±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005216 IEA ion channel activity
GO:0005245 IDA voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005516 IPI calmodulin binding
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005891 IDA voltage-gated calcium channel complex
GO:0006112 TAS energy reserve metabolic process
GO:0006811 IEA ion transport
GO:0007204 IDA positive regulation of cytosolic calcium ion concentration
GO:0007411 TAS axon guidance
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0010881 TAS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014069 IDA postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IDA integral component of membrane
GO:0030018 ISS Z disc
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035585 TAS calcium-mediated signaling using extracellular calcium source
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0050796 TAS regulation of insulin secretion
GO:0051393 IPI alpha-actinin binding
GO:0055085 IEA transmembrane transport
GO:0060402 TAS calcium ion transport into cytosol
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential
GO:0086064 TAS cell communication by electrical coupling involved in cardiac conduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000187474 Cacna1c-008 protein_coding Mus_musculus 0 8408
ENSMUST00000075591 Cacna1c-024 protein_coding Mus_musculus 0 8357
ENSMUST00000078320 Cacna1c-004 protein_coding Mus_musculus 0 8357
ENSMUST00000186889 Cacna1c-001 protein_coding Mus_musculus 0 8287
ENSMUST00000187940 Cacna1c-002 protein_coding Mus_musculus 0 8231
ENSMUST00000112790 Cacna1c-005 protein_coding Mus_musculus 0 8179
ENSMUST00000188078 Cacna1c-015 protein_coding Mus_musculus 0 8139
ENSMUST00000188865 Cacna1c-020 protein_coding Mus_musculus 0 7962
ENSMUST00000190285 Cacna1c-007 protein_coding Mus_musculus 0 6532
ENSMUST00000188522 Cacna1c-014 protein_coding Mus_musculus 0 6505
ENSMUST00000187386 Cacna1c-006 protein_coding Mus_musculus 0 6451
ENSMUST00000189389 Cacna1c-016 protein_coding Mus_musculus 0 5171
ENSMUST00000189520 Cacna1c-017 protein_coding Mus_musculus 0 5049
ENSMUST00000185345 Cacna1c-019 protein_coding Mus_musculus 0 4484
ENSMUST00000187317 Cacna1c-018 protein_coding Mus_musculus 0 3611
ENSMUST00000188106 Cacna1c-011 protein_coding Mus_musculus 0 3544
ENSMUST00000112793 Cacna1c-010 protein_coding Mus_musculus 0 3306
ENSMUST00000112825 Cacna1c-201 protein_coding Mus_musculus 0 3083
ENSMUST00000188181 Cacna1c-012 processed_transcript Mus_musculus 0 3083
ENSDART00000132909 cacna1c-001 protein_coding Danio_rerio 0 2410
ENSDART00000028856 cacna1c-201 protein_coding Danio_rerio 0 2290
ENSMUST00000112250 Cacna1d-202 protein_coding Mus_musculus 0 1068
ENSMUST00000112249 Cacna1d-201 protein_coding Mus_musculus 0 1068
ENSMUST00000112064 Cacna1s-201 protein_coding Mus_musculus 0 776
ENSMUST00000161865 Cacna1s-003 protein_coding Mus_musculus 0 776
ENSMUST00000112068 Cacna1s-001 protein_coding Mus_musculus 0 776
ENSMUST00000160641 Cacna1s-002 protein_coding Mus_musculus 0 776
ENSMUST00000189057 Cacna1c-003 processed_transcript Mus_musculus 0 534
ENSMUST00000191196 Cacna1c-021 processed_transcript Mus_musculus 0 481
ENSMUST00000187849 Cacna1c-023 processed_transcript Mus_musculus 0 472
ENSDART00000041564 cacna1fb-201 protein_coding Danio_rerio 0 396
ENSDART00000134151 cacna1fb-001 protein_coding Danio_rerio 0 396
ENSDART00000062406 cacna1sb-001 protein_coding Danio_rerio 0 361
ENSMUST00000155090 Cacna1f-003 nonsense_mediated_decay Mus_musculus 0 1147
ENSMUST00000115726 Cacna1f-001 protein_coding Mus_musculus 0 1147
ENSMUST00000115725 Cacna1f-002 protein_coding Mus_musculus 0 669
ENSMUST00000141634 Cacna1f-004 retained_intron Mus_musculus 0 1147
ENSDART00000105895 cacna1sa-001 protein_coding Danio_rerio 0 396

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