ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: sodium channel, voltage-gated, type V, alpha subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000413689 SCN5A-001 ENSG00000183873 9606 - 3:38548062-38649672 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000413689
Transcript ID HAoEC HUVEC
ENST00000413689 0.803±0.62 0.489±0.21

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0003231 IEA cardiac ventricle development
GO:0005216 IEA ion channel activity
GO:0005248 IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IEA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 IEA sodium ion transport
GO:0009986 IEA cell surface
GO:0014070 IEA response to organic cyclic compound
GO:0014704 IEA intercalated disc
GO:0016020 IEA membrane
GO:0030315 IEA T-tubule
GO:0034706 IEA sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0055085 IEA transmembrane transport
GO:0086004 IEA regulation of cardiac muscle cell contraction
GO:0086006 IEA voltage-gated sodium channel activity involved in cardiac muscle cell action potential
GO:0086012 IEA membrane depolarization during cardiac muscle cell action potential
GO:0086046 IEA membrane depolarization during SA node cell action potential
GO:0086063 IEA voltage-gated sodium channel activity involved in SA node cell action potential
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:0097110 IEA scaffold protein binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000117911 Scn5a-001 protein_coding Mus_musculus 0 7854
ENSMUST00000120420 Scn5a-002 protein_coding Mus_musculus 0 7697
ENSMUST00000065196 Scn5a-201 protein_coding Mus_musculus 0 7561
ENSMUST00000084787 Scn10a-201 protein_coding Mus_musculus 0 1565
ENSMUST00000021056 Scn4a-001 protein_coding Mus_musculus 0 1495
ENSMUST00000100067 Scn2a1-201 protein_coding Mus_musculus 0 1079
ENSMUST00000028377 Scn2a1-001 protein_coding Mus_musculus 0 1079
ENSMUST00000169900 Scn9a-203 protein_coding Mus_musculus 0 966
ENSMUST00000100063 Scn9a-201 protein_coding Mus_musculus 0 966
ENSMUST00000164384 Scn9a-202 protein_coding Mus_musculus 0 966
ENSMUST00000112354 Scn9a-002 protein_coding Mus_musculus 0 966
ENSMUST00000100064 Scn9a-001 protein_coding Mus_musculus 0 966
ENSMUST00000066432 Scn3a-201 protein_coding Mus_musculus 0 870
ENSMUST00000100069 Scn3a-001 protein_coding Mus_musculus 0 870
ENSMUST00000112371 Scn1a-201 protein_coding Mus_musculus 0 737
ENSMUST00000094951 Scn1a-005 protein_coding Mus_musculus 0 737
ENSMUST00000077489 Scn1a-004 protein_coding Mus_musculus 0 737
ENSMUST00000112366 Scn1a-001 protein_coding Mus_musculus 0 737
ENSMUST00000156865 Scn1a-003 protein_coding Mus_musculus 0 483
ENSDART00000022761 scn8ab-201 protein_coding Danio_rerio 0 399
ENSDART00000151299 scn8ab-001 protein_coding Danio_rerio 0 399
ENSMUST00000126837 Scn3a-002 protein_coding Mus_musculus 0 318
ENSMUST00000144254 Scn2a1-004 protein_coding Mus_musculus 0 217
ENSMUST00000138934 Scn5a-003 protein_coding Mus_musculus 0 196
ENSMUST00000138368 Scn2a1-003 retained_intron Mus_musculus 5.04467e-44 185

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