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Transcript Info |
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Description: | Raf-1 proto-oncogene, serine/threonine kinase | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000442415 ![]() |
RAF1-007 |
ENSG00000132155 ![]() |
9606 | - |
3:12583798-12664148 |
protein_coding |
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Expression PatternsNo expression data. |
Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0000165 | TAS | MAPK cascade |
GO:0000186 | TAS | activation of MAPKK activity |
GO:0004672 | TAS:IEA | protein kinase activity |
GO:0004674 | IDA | protein serine/threonine kinase activity |
GO:0004713 | IEA | protein tyrosine kinase activity |
GO:0005057 | IEA | receptor signaling protein activity |
GO:0005515 | IPI | protein binding |
GO:0005524 | IEA | ATP binding |
GO:0005634 | IEA | nucleus |
GO:0005737 | ISS | cytoplasm |
GO:0005741 | TAS | mitochondrial outer membrane |
GO:0005794 | IPI | Golgi apparatus |
GO:0005829 | IDA | cytosol |
GO:0005886 | IDA | plasma membrane |
GO:0006468 | IEA | protein phosphorylation |
GO:0006915 | TAS | apoptotic process |
GO:0007165 | TAS:IEA | signal transduction |
GO:0007173 | TAS | epidermal growth factor receptor signaling pathway |
GO:0007190 | NAS | activation of adenylate cyclase activity |
GO:0007264 | TAS | small GTPase mediated signal transduction |
GO:0007265 | TAS | Ras protein signal transduction |
GO:0007268 | TAS | synaptic transmission |
GO:0007411 | TAS | axon guidance |
GO:0007596 | TAS | blood coagulation |
GO:0008283 | TAS | cell proliferation |
GO:0008285 | IDA | negative regulation of cell proliferation |
GO:0008286 | TAS | insulin receptor signaling pathway |
GO:0008543 | TAS | fibroblast growth factor receptor signaling pathway |
GO:0016772 | IEA | transferase activity, transferring phosphorus-containing groups |
GO:0030168 | TAS | platelet activation |
GO:0031333 | IDA | negative regulation of protein complex assembly |
GO:0033138 | IDA | positive regulation of peptidyl-serine phosphorylation |
GO:0034220 | TAS | ion transmembrane transport |
GO:0035023 | TAS | regulation of Rho protein signal transduction |
GO:0035556 | IEA | intracellular signal transduction |
GO:0038095 | TAS | Fc-epsilon receptor signaling pathway |
GO:0042060 | TAS | wound healing |
GO:0042802 | IPI | identical protein binding |
GO:0042981 | TAS | regulation of apoptotic process |
GO:0043066 | IDA | negative regulation of apoptotic process |
GO:0043154 | TAS | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
GO:0045087 | TAS | innate immune response |
GO:0045595 | TAS | regulation of cell differentiation |
GO:0046872 | IEA | metal ion binding |
GO:0048011 | TAS | neurotrophin TRK receptor signaling pathway |
GO:0055085 | TAS | transmembrane transport |
GO:2000145 | TAS | regulation of cell motility |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000000451
![]() |
Raf1-001 | protein_coding | Mus_musculus | 0 | 1543 |
ENSMUST00000112949
![]() |
Raf1-003 | protein_coding | Mus_musculus | 0 | 1543 |
ENSMUST00000127503
![]() |
Raf1-002 | retained_intron | Mus_musculus | 0 | 1216 |
ENSMUST00000124553
![]() |
Raf1-005 | processed_transcript | Mus_musculus | 0 | 833 |
ENSMUST00000130528
![]() |
Raf1-006 | retained_intron | Mus_musculus | 0 | 830 |
ENSMUST00000147979
![]() |
Raf1-004 | protein_coding | Mus_musculus | 0 | 773 |