ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: MDM4, p53 regulator
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000454264 MDM4-203 ENSG00000198625 9606 + 1:204516379-204558119 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HMVEC-DHUVECENST00000454264
Transcript ID HMVEC-D HUVEC
ENST00000454264 1.293±0.00 0.860±0.53

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA:NAS nucleus
GO:0006461 IDA protein complex assembly
GO:0008270 IEA:TAS zinc ion binding
GO:0008283 IEP cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0019899 IPI enzyme binding
GO:0030330 IEP DNA damage response, signal transduction by p53 class mediator
GO:0042177 IMP negative regulation of protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0045023 IEP G0 to G1 transition
GO:0050821 IEP protein stabilization
GO:0071157 IEA negative regulation of cell cycle arrest
GO:0071456 IEP cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000188090 Mdm4-001 protein_coding Mus_musculus 0 813
ENSMUST00000186617 Mdm4-006 protein_coding Mus_musculus 0 804
ENSMUST00000067398 Mdm4-003 protein_coding Mus_musculus 0 793
ENSMUST00000067429 Mdm4-005 protein_coding Mus_musculus 0 754
ENSMUST00000185398 Mdm4-004 nonsense_mediated_decay Mus_musculus 0 619
ENSMUST00000191212 Mdm4-002 nonsense_mediated_decay Mus_musculus 0 619
ENSMUST00000121299 Mdm4-ps-001 processed_pseudogene Mus_musculus 0 569
ENSMUST00000190312 Mdm4-011 processed_transcript Mus_musculus 0 532
ENSMUST00000185418 Mdm4-010 retained_intron Mus_musculus 0 444
ENSMUST00000190807 Mdm4-009 protein_coding Mus_musculus 0 387
ENSMUST00000187529 Mdm4-013 retained_intron Mus_musculus 0 265
ENSMUST00000189596 Mdm4-012 retained_intron Mus_musculus 0 263
ENSMUST00000186513 Mdm4-008 retained_intron Mus_musculus 4.00001e-41 176
ENSMUST00000034431 Tmem170-201 protein_coding Mus_musculus 0.00000008 66

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