ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: retinoid X receptor, alpha
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000481739 RXRA-002 ENSG00000186350 9606 + 9:134326580-134437019 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000481739
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000481739 7.446±0.00 5.304±1.15 4.349±0.00 7.551±7.20

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IDA nuclear chromatin
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001701 IEA in utero embryonic development
GO:0001890 IEA placenta development
GO:0001893 IEA maternal placenta development
GO:0003677 IDA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0003708 TAS retinoic acid receptor activity
GO:0003713 TAS transcription coactivator activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004886 IEA 9-cis retinoic acid receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006766 TAS vitamin metabolic process
GO:0007566 IEA embryo implantation
GO:0008134 IEA transcription factor binding
GO:0008203 TAS cholesterol metabolic process
GO:0008270 IEA zinc ion binding
GO:0010467 TAS gene expression
GO:0019048 IDA modulation by virus of host morphology or physiology
GO:0019899 IPI enzyme binding
GO:0031490 IEA chromatin DNA binding
GO:0032526 IMP response to retinoic acid
GO:0035357 IDA peroxisome proliferator activated receptor signaling pathway
GO:0042809 IPI vitamin D receptor binding
GO:0043010 IEA camera-type eye development
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IEA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044255 TAS cellular lipid metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0044323 IDA retinoic acid-responsive element binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045994 IEA positive regulation of translational initiation by iron
GO:0046982 IDA protein heterodimerization activity
GO:0048384 IMP retinoic acid receptor signaling pathway
GO:0051289 IDA protein homotetramerization
GO:0055010 IEA ventricular cardiac muscle tissue morphogenesis
GO:0055012 IEA ventricular cardiac muscle cell differentiation
GO:0060528 IEA secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development
GO:0060687 IEA regulation of branching involved in prostate gland morphogenesis
GO:0070644 IDA vitamin D response element binding
GO:1901522 IEA positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000166775 Rxra-201 protein_coding Mus_musculus 0 1746
ENSMUST00000077257 Rxra-001 protein_coding Mus_musculus 0 1740
ENSMUST00000100251 Rxra-002 protein_coding Mus_musculus 0 1629
ENSMUST00000113934 Rxra-003 protein_coding Mus_musculus 0 1626
ENSMUST00000148756 Rxra-005 processed_transcript Mus_musculus 0 508
ENSDART00000009755 rxrba-201 protein_coding Danio_rerio 0 464
ENSDART00000102075 rxrba-004 protein_coding Danio_rerio 0 464
ENSDART00000136528 rxrba-003 protein_coding Danio_rerio 0 464
ENSDART00000132887 rxrba-005 protein_coding Danio_rerio 0 241
ENSDART00000147429 rxrba-007 protein_coding Danio_rerio 0 239

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