ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: dicer 1, ribonuclease type III
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000526495 DICER1-004 ENSG00000100697 9606 - 14:95086228-95158010 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000526495
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000526495 1.379±0.86 1.392±0.00 2.017±1.17

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001525 IEA angiogenesis
GO:0001942 IEA hair follicle development
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0003725 IDA double-stranded RNA binding
GO:0004386 IEA helicase activity
GO:0004525 IDA:IEA ribonuclease III activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0005793 IEA endoplasmic reticulum-Golgi intermediate compartment
GO:0005829 TAS cytosol
GO:0006396 IEA RNA processing
GO:0008283 IEA cell proliferation
GO:0009791 IEA post-embryonic development
GO:0010070 IEA zygote asymmetric cell division
GO:0010467 TAS gene expression
GO:0010468 IEA regulation of gene expression
GO:0010626 ISS negative regulation of Schwann cell proliferation
GO:0010628 IEA positive regulation of gene expression
GO:0010660 IEA regulation of muscle cell apoptotic process
GO:0014040 ISS positive regulation of Schwann cell differentiation
GO:0014835 IEA myoblast differentiation involved in skeletal muscle regeneration
GO:0016442 IDA RISC complex
GO:0016787 IEA hydrolase activity
GO:0016891 IEA endoribonuclease activity, producing 5'-phosphomonoesters
GO:0019827 IEA stem cell maintenance
GO:0021522 IEA spinal cord motor neuron differentiation
GO:0021675 ISS nerve development
GO:0021889 IEA olfactory bulb interneuron differentiation
GO:0021987 IEA cerebral cortex development
GO:0030324 IEA lung development
GO:0030326 IEA embryonic limb morphogenesis
GO:0030422 IDA production of siRNA involved in RNA interference
GO:0030423 IMP targeting of mRNA for destruction involved in RNA interference
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030426 IEA growth cone
GO:0031054 IDA pre-miRNA processing
GO:0031069 IEA hair follicle morphogenesis
GO:0031641 IEA regulation of myelination
GO:0031643 ISS positive regulation of myelination
GO:0032290 ISS peripheral nervous system myelin formation
GO:0035068 IEA micro-ribonucleoprotein complex
GO:0035116 IEA embryonic hindlimb morphogenesis
GO:0035196 ISS production of miRNAs involved in gene silencing by miRNA
GO:0035198 IEA miRNA binding
GO:0035264 IEA multicellular organism growth
GO:0042487 IEA regulation of odontogenesis of dentin-containing tooth
GO:0045069 IEA regulation of viral genome replication
GO:0045595 IEA regulation of cell differentiation
GO:0045664 IEA regulation of neuron differentiation
GO:0046872 IEA metal ion binding
GO:0048255 IEA mRNA stabilization
GO:0048536 IEA spleen development
GO:0048565 IEA digestive tract development
GO:0048608 IEA reproductive structure development
GO:0048713 IEA regulation of oligodendrocyte differentiation
GO:0048730 IEA epidermis morphogenesis
GO:0048754 IEA branching morphogenesis of an epithelial tube
GO:0048812 ISS neuron projection morphogenesis
GO:0048856 IEA anatomical structure development
GO:0050767 IEA regulation of neurogenesis
GO:0051216 IEA cartilage development
GO:0051225 IEA spindle assembly
GO:0051252 IEA regulation of RNA metabolic process
GO:0051607 IEA defense response to virus
GO:0051726 IEA regulation of cell cycle
GO:0055013 IEA cardiac muscle cell development
GO:0060119 IEA inner ear receptor cell development
GO:0060576 IEA intestinal epithelial cell development
GO:0061309 IEA cardiac neural crest cell development involved in outflow tract morphogenesis
GO:0061548 IEA ganglion development
GO:0070173 IEA regulation of enamel mineralization
GO:0071335 IEA hair follicle cell proliferation
GO:0090501 IDA RNA phosphodiester bond hydrolysis
GO:0090502 IEA RNA phosphodiester bond hydrolysis, endonucleolytic
GO:2000628 IEA regulation of miRNA metabolic process
GO:2000630 IEA positive regulation of miRNA metabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000041987 Dicer1-201 protein_coding Mus_musculus 0 7232
ENSDART00000109826 dicer1-201 protein_coding Danio_rerio 0 606
ENSDART00000045881 dicer1-001 protein_coding Danio_rerio 0 606

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