ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: MDM2 proto-oncogene, E3 ubiquitin protein ligase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000539479 MDM2-012 ENSG00000135679 9606 + 12:68809017-68835933 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000539479
Transcript ID HUVEC
ENST00000539479 35.094±13.64

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005730 IDA nucleolus
GO:0042787 IMP protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0071157 IEA negative regulation of cell cycle arrest

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020408 Mdm2-001 protein_coding Mus_musculus 0 577
ENSMUST00000132277 Mdm2-004 retained_intron Mus_musculus 0 409
ENSMUST00000155285 Mdm2-003 nonsense_mediated_decay Mus_musculus 0 409
ENSMUST00000105263 Mdm2-002 protein_coding Mus_musculus 9e-28 128

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