ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: interferon regulatory factor 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000601291 IRF3-002 ENSG00000126456 9606 - 19:49659572-49665802 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000601291
Transcript ID HUVEC
ENST00000601291 5.671±3.56

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000975 IEA regulatory region DNA binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 NAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003712 TAS transcription cofactor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006915 TAS apoptotic process
GO:0006974 TAS cellular response to DNA damage stimulus
GO:0009617 IEA response to bacterium
GO:0016032 IEA viral process
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0031663 IEA lipopolysaccharide-mediated signaling pathway
GO:0032480 TAS negative regulation of type I interferon production
GO:0032481 TAS positive regulation of type I interferon production
GO:0032496 IEA response to lipopolysaccharide
GO:0032727 ISS positive regulation of interferon-alpha production
GO:0032728 ISS positive regulation of interferon-beta production
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0039530 TAS MDA-5 signaling pathway
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043330 IEA response to exogenous dsRNA
GO:0044212 IEA transcription regulatory region DNA binding
GO:0045087 TAS innate immune response
GO:0045351 IEA type I interferon biosynthetic process
GO:0045358 IEA negative regulation of interferon-beta biosynthetic process
GO:0050689 IEA negative regulation of defense response to virus by host
GO:0050715 IEA positive regulation of cytokine secretion
GO:0051607 ISS defense response to virus
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway
GO:0060340 IEA positive regulation of type I interferon-mediated signaling pathway
GO:0071359 IEA cellular response to dsRNA
GO:0071888 TAS macrophage apoptotic process
GO:0097300 IEA programmed necrotic cell death

Homologs

No Homologs available.

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