Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
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$value = array(
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)
$config = '_cake_core_'
$settings = array(
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	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
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	'isWindows' => false,
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	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
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$config = '_cake_model_'
$settings = array(
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	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
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$value = array(
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	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
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$config = '_cake_model_'
$settings = array(
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	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
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	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
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$value = null
$config = '_cake_model_'
$settings = array(
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	'engine' => 'File',
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	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
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	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
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$config = '_cake_model_'
$settings = array(
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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Transcript Info
Description:	histone cluster 1, H4a
Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
ENST00000617569	HIST1H4A-001	ENSG00000278637	9606	+	6:26021679-26021990	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID HAoEC HHSEC HUVEC ENST00000617569 7.389±11.98 1.888±0.00 21.049±41.41

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0000228	IDA	nuclear chromosome
GO:0000278	TAS	mitotic cell cycle
GO:0000723	TAS	telomere maintenance
GO:0000786	TAS:IEA	nucleosome
GO:0003677	TAS:IEA	DNA binding
GO:0005515	IPI	protein binding
GO:0005576	TAS	extracellular region
GO:0005634	IDA:IEA	nucleus
GO:0005654	TAS	nucleoplasm
GO:0006325	TAS	chromatin organization
GO:0006334	TAS	nucleosome assembly
GO:0006335	IDA	DNA replication-dependent nucleosome assembly
GO:0006336	IDA	DNA replication-independent nucleosome assembly
GO:0006352	IEA	DNA-templated transcription, initiation
GO:0016020	IDA	membrane
GO:0034080	TAS	CENP-A containing nucleosome assembly
GO:0035574	TAS	histone H4-K20 demethylation
GO:0035575	TAS	histone demethylase activity (H4-K20 specific)
GO:0043234	IDA	protein complex
GO:0044822	IDA	poly(A) RNA binding
GO:0045653	IDA	negative regulation of megakaryocyte differentiation
GO:0046982	IEA	protein heterodimerization activity
GO:0070062	IDA	extracellular vesicular exosome

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSDART00000112685	HIST4H4-201	protein_coding	Danio_rerio	0	278
ENSDART00000112196	si:ch73-36p18.4-001	protein_coding	Danio_rerio	0	278
ENSDART00000128564	si:ch211-113a14.26-001	protein_coding	Danio_rerio	0	272
ENSDART00000121786	si:ch211-113a14.6-001	protein_coding	Danio_rerio	0	267
ENSDART00000121825	HIST1H4I-201	protein_coding	Danio_rerio	0	246
ENSDART00000154389	HIST1H4I-001	protein_coding	Danio_rerio	0	246

Loading

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Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

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Code Context
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$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??