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ANGIOGENES

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000013095 gclc 7955 - 13:2261361-2296388 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000017148 gclc-001 2261361-2296388 protein_coding
  ENSDART00000126697 gclc-201 2261362-2296122 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; LECsUnknown1Unknown2ENSDART00000017148ENSDART00000126697
Transcript ID LECs Unknown1 Unknown2
ENSDART00000017148 N/A 23.319±0.00 16.841±0.00
ENSDART00000126697 6.309±6.88 N/A 6.780±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000585 CIL_000585_0001 CGP
CIL_000588 CIL_000588_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 ISS magnesium ion binding
GO:0004357 IEA glutamate-cysteine ligase activity
GO:0005737 IBA cytoplasm
GO:0006534 ISS cysteine metabolic process
GO:0006536 ISS glutamate metabolic process
GO:0006750 IEA glutathione biosynthetic process
GO:0006979 ISS response to oxidative stress
GO:0009408 ISS response to heat
GO:0009725 ISS response to hormone
GO:0016595 ISS glutamate binding
GO:0016874 IEA ligase activity
GO:0043066 ISS negative regulation of apoptotic process
GO:0043531 ISS ADP binding
GO:0045454 ISS cell redox homeostasis
GO:0045892 ISS negative regulation of transcription, DNA-dependent
GO:0050662 ISS coenzyme binding
GO:0050880 ISS regulation of blood vessel size

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000001084 GCLC glutamate-cysteine ligase, catalytic subunit protein_coding Homo_sapiens
ENSMUSG00000032350 Gclc protein_coding Mus_musculus

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