ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sodium channel, voltage-gated, type IV, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000007314 SCN4A 9606 - 17:63938554-63972918 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000435607 SCN4A-201 63938554-63972918 protein_coding
  ENST00000578147 SCN4A-001 63938554-63972918 protein_coding
  ENST00000581514 SCN4A-002 63959373-63961693 retained_intron
  ENST00000584310 SCN4A-003 63947954-63949704 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000435607ENST00000578147ENST00000581514
Transcript ID HAoEC HUVEC
ENST00000435607 0.084±0.16 0.005±0.00
ENST00000578147 0.004±0.00 0.005±0.00
ENST00000581514 0.071±0.00 0.122±0.07

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0009B9 CIL_0009B9_0001 VISTA
CIL_0006Q8 CIL_0006Q8_0001 CGP
CIL_0002P3 CIL_0002P3_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IBA:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0006936 TAS muscle contraction
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IBA sodium ion transmembrane transport
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034588 scn4ab protein_coding Danio_rerio
ENSMUSG00000001027 Scn4a protein_coding Mus_musculus

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