ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: sodium channel, voltage-gated, type IV, alpha subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000435607 SCN4A-201 ENSG00000007314 9606 - 17:63938554-63972918 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000435607
Transcript ID HAoEC HUVEC
ENST00000435607 0.084±0.16 0.005±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 IBA:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0006936 TAS muscle contraction
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IBA sodium ion transmembrane transport
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000021056 Scn4a-001 protein_coding Mus_musculus 0 6660
ENSMUST00000065196 Scn5a-201 protein_coding Mus_musculus 0 1639
ENSMUST00000120420 Scn5a-002 protein_coding Mus_musculus 0 1639
ENSMUST00000117911 Scn5a-001 protein_coding Mus_musculus 0 1639
ENSMUST00000108908 Scn8a-002 protein_coding Mus_musculus 0 1402
ENSMUST00000108910 Scn8a-202 protein_coding Mus_musculus 0 1402
ENSMUST00000082209 Scn8a-201 protein_coding Mus_musculus 0 1402
ENSMUST00000100067 Scn2a1-201 protein_coding Mus_musculus 0 1199
ENSMUST00000028377 Scn2a1-001 protein_coding Mus_musculus 0 1199
ENSMUST00000066432 Scn3a-201 protein_coding Mus_musculus 0 1177
ENSMUST00000100069 Scn3a-001 protein_coding Mus_musculus 0 1177
ENSMUST00000084787 Scn10a-201 protein_coding Mus_musculus 0 1099
ENSDART00000090994 scn1lab-201 protein_coding Danio_rerio 0 961
ENSDART00000151247 scn1lab-001 protein_coding Danio_rerio 0 961
ENSMUST00000108909 Scn8a-001 protein_coding Mus_musculus 0 628
ENSDART00000022761 scn8ab-201 protein_coding Danio_rerio 0 562
ENSDART00000151299 scn8ab-001 protein_coding Danio_rerio 0 562
ENSMUST00000112371 Scn1a-201 protein_coding Mus_musculus 0 558
ENSMUST00000094951 Scn1a-005 protein_coding Mus_musculus 0 558
ENSMUST00000077489 Scn1a-004 protein_coding Mus_musculus 0 558
ENSMUST00000112366 Scn1a-001 protein_coding Mus_musculus 0 558
ENSDART00000022382 scn12aa-201 protein_coding Danio_rerio 0 403
ENSMUST00000144254 Scn2a1-004 protein_coding Mus_musculus 0 291
ENSDART00000104004 scn4ab-201 protein_coding Danio_rerio 0 287
ENSDART00000044157 scn4ab-001 protein_coding Danio_rerio 0 285
ENSMUST00000126837 Scn3a-002 protein_coding Mus_musculus 0 283
ENSMUST00000138368 Scn2a1-003 retained_intron Mus_musculus 0 207

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