ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: nuclear factor I/X (CCAAT-binding transcription factor)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000008441 NFIX 9606 + 19:12995608-13098796 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358552 NFIX-201 13024580-13098766 protein_coding
  ENST00000360105 NFIX-003 13024580-13098796 protein_coding
  ENST00000397661 NFIX-001 12995608-13096201 protein_coding
  ENST00000585382 NFIX-009 13012207-13081835 nonsense_mediated_decay
  ENST00000585575 NFIX-006 13024032-13094649 protein_coding
  ENST00000586797 NFIX-005 13024585-13094684 nonsense_mediated_decay
  ENST00000586873 NFIX-011 13024627-13025510 protein_coding
  ENST00000587260 NFIX-007 13024939-13094770 protein_coding
  ENST00000587760 NFIX-002 13023991-13094758 protein_coding
  ENST00000588228 NFIX-004 13024581-13094755 protein_coding
  ENST00000588680 NFIX-012 13070003-13074019 processed_transcript
  ENST00000590027 NFIX-008 13012188-13025520 protein_coding
  ENST00000591028 NFIX-010 13024613-13025495 protein_coding
  ENST00000592199 NFIX-013 12995838-13094649 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000358552ENST00000360105ENST00000397661ENST00000585575ENST00000587260ENST00000587760ENST00000588228ENST00000592199
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000358552 N/A N/A N/A 0.920±0.35
ENST00000360105 4.390±0.00 4.830±3.60 N/A 1.675±1.24
ENST00000397661 N/A 2.244±0.77 2.542±0.00 1.564±0.88
ENST00000585575 N/A N/A N/A 0.011±0.00
ENST00000587260 N/A 3.670±0.20 N/A 0.113±0.00
ENST00000587760 N/A 5.848±2.30 3.716±0.00 2.570±2.05
ENST00000588228 N/A N/A N/A 0.056±0.00
ENST00000592199 N/A N/A N/A 0.492±0.42

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007VV CIL_0007VV_0001 VISTA
CIL_0007ZV CIL_0007ZV_0001 VISTA
CIL_0001IU CIL_0001IU_0002 CGP
CIL_0004F9 CIL_0004F9_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0006260 IEA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0021549 IEA cerebellum development
GO:0021680 IEA cerebellar Purkinje cell layer development
GO:0021707 IEA cerebellar granule cell differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048708 IEA astrocyte differentiation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043226 nfixa protein_coding Danio_rerio
ENSDARG00000061836 nfixb protein_coding Danio_rerio
ENSMUSG00000001911 Nfix protein_coding Mus_musculus

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