ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: polynucleotide kinase 3'-phosphatase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000039650 PNKP 9606 - 19:49861204-49867909 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000322344 PNKP-001 49861204-49867565 protein_coding
  ENST00000593706 PNKP-011 49861878-49864062 retained_intron
  ENST00000593946 PNKP-005 49861232-49867228 nonsense_mediated_decay
  ENST00000594661 PNKP-006 49861204-49867001 retained_intron
  ENST00000595081 PNKP-015 49861204-49861896 retained_intron
  ENST00000595792 PNKP-009 49866141-49867561 processed_transcript
  ENST00000596014 PNKP-004 49861231-49867286 protein_coding
  ENST00000596726 PNKP-008 49867115-49867883 protein_coding
  ENST00000597965 PNKP-016 49861253-49861698 protein_coding
  ENST00000598020 PNKP-010 49865252-49867533 nonsense_mediated_decay
  ENST00000599454 PNKP-014 49861205-49862075 retained_intron
  ENST00000599543 PNKP-007 49866399-49867909 protein_coding
  ENST00000600573 PNKP-002 49861240-49867576 protein_coding
  ENST00000600910 PNKP-003 49861239-49867555 protein_coding
  ENST00000601816 PNKP-013 49861278-49862209 retained_intron

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000322344ENST00000593706ENST00000593946ENST00000594661ENST00000596014ENST00000599454ENST00000599543ENST00000600573
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000322344 23.705±7.07 6.864±2.25 16.053±0.00 N/A 8.290±5.63
ENST00000593706 N/A N/A N/A 6.987±0.00 N/A
ENST00000593946 N/A 2.820±0.00 N/A N/A 3.888±0.00
ENST00000594661 N/A 1.483±0.23 N/A 2.076±0.00 1.850±1.41
ENST00000596014 11.139±0.00 6.183±3.04 9.331±0.00 9.987±0.00 4.666±3.70
ENST00000599454 50.808±15.35 N/A 31.228±0.00 N/A 8.232±0.48
ENST00000599543 N/A N/A N/A N/A 8.127±0.00
ENST00000600573 N/A 3.268±0.49 N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000718 NAS nucleotide-excision repair, DNA damage removal
GO:0003684 NAS damaged DNA binding
GO:0003690 TAS double-stranded DNA binding
GO:0004519 NAS endonuclease activity
GO:0005515 IPI:IEA protein binding
GO:0005524 NAS ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006261 NAS DNA-dependent DNA replication
GO:0006281 IGI DNA repair
GO:0006979 IDA response to oxidative stress
GO:0009314 TAS response to radiation
GO:0016020 IDA membrane
GO:0016311 IDA dephosphorylation
GO:0017076 NAS purine nucleotide binding
GO:0019201 IDA nucleotide kinase activity
GO:0042769 IDA DNA damage response, detection of DNA damage
GO:0046403 IDA polynucleotide 3'-phosphatase activity
GO:0046404 IDA ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
GO:0046939 IDA nucleotide phosphorylation
GO:0090305 NAS nucleic acid phosphodiester bond hydrolysis
GO:0098506 IEA polynucleotide 3' dephosphorylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000002963 Pnkp protein_coding Mus_musculus

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