ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: polynucleotide kinase 3'-phosphatase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000322344 PNKP-001 ENSG00000039650 9606 - 19:49861204-49867565 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000322344
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000322344 23.705±7.07 6.864±2.25 16.053±0.00 8.290±5.63

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000718 NAS nucleotide-excision repair, DNA damage removal
GO:0003684 NAS damaged DNA binding
GO:0003690 TAS double-stranded DNA binding
GO:0004519 NAS endonuclease activity
GO:0005515 IPI:IEA protein binding
GO:0005524 NAS ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0006261 NAS DNA-dependent DNA replication
GO:0006281 IGI DNA repair
GO:0006979 IDA response to oxidative stress
GO:0009314 TAS response to radiation
GO:0016020 IDA membrane
GO:0016311 IDA dephosphorylation
GO:0017076 NAS purine nucleotide binding
GO:0019201 IDA nucleotide kinase activity
GO:0042769 IDA DNA damage response, detection of DNA damage
GO:0046403 IDA polynucleotide 3'-phosphatase activity
GO:0046404 IDA ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity
GO:0046939 IDA nucleotide phosphorylation
GO:0090305 NAS nucleic acid phosphodiester bond hydrolysis
GO:0098506 IEA polynucleotide 3' dephosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003044 Pnkp-001 protein_coding Mus_musculus 0 1160
ENSMUST00000107876 Pnkp-002 protein_coding Mus_musculus 0 1160
ENSMUST00000123015 Pnkp-005 nonsense_mediated_decay Mus_musculus 0 745
ENSMUST00000098478 Pnkp-004 protein_coding Mus_musculus 0 593
ENSMUST00000145850 Pnkp-003 retained_intron Mus_musculus 0 593

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