ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: myocyte enhancer factor 2A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000449277 MEF2A-004 ENSG00000068305 9606 + 15:99565990-99716406 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHHSECHUVECENST00000449277
Transcript ID BECs HHSEC HUVEC
ENST00000449277 1.537±0.00 6.642±0.00 3.708±1.59

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000002 ISS mitochondrial genome maintenance
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000165 IDA MAPK cascade
GO:0000790 ISS nuclear chromatin
GO:0000977 IDA RNA polymerase II regulatory region sequence-specific DNA binding
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002756 TAS MyD88-independent toll-like receptor signaling pathway
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006351 IDA transcription, DNA-templated
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006915 IEA apoptotic process
GO:0007507 IEP heart development
GO:0007517 NAS muscle organ development
GO:0033613 IPI activating transcription factor binding
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034138 TAS toll-like receptor 3 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034146 TAS toll-like receptor 5 signaling pathway
GO:0034162 TAS toll-like receptor 9 signaling pathway
GO:0034166 TAS toll-like receptor 10 signaling pathway
GO:0035035 IPI histone acetyltransferase binding
GO:0035666 TAS TRIF-dependent toll-like receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042692 TAS muscle cell differentiation
GO:0042826 IPI histone deacetylase binding
GO:0043565 IDA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IPI SMAD binding
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048311 ISS mitochondrion distribution
GO:0048813 ISS dendrite morphogenesis
GO:0051149 TAS positive regulation of muscle cell differentiation
GO:0051403 TAS stress-activated MAPK cascade
GO:0055005 ISS ventricular cardiac myofibril assembly
GO:0061337 ISS cardiac conduction
GO:0070375 IMP ERK5 cascade
GO:0071277 IDA cellular response to calcium ion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000156690 Mef2a-002 protein_coding Mus_musculus 0 5421
ENSMUST00000107476 Mef2a-004 protein_coding Mus_musculus 0 4708
ENSMUST00000072460 Mef2a-001 nonsense_mediated_decay Mus_musculus 0 2521
ENSMUST00000076325 Mef2a-003 protein_coding Mus_musculus 0 2460
ENSMUST00000032776 Mef2a-005 protein_coding Mus_musculus 0 2191
ENSMUST00000135493 Mef2a-007 nonsense_mediated_decay Mus_musculus 0 1541
ENSMUST00000133074 Mef2a-006 protein_coding Mus_musculus 0 654

Loading