ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SMG6 nonsense mediated mRNA decay factor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000070366 SMG6 9606 - 17:2059839-2303771 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263073 SMG6-001 2059843-2303771 protein_coding
  ENST00000354901 SMG6-002 2059850-2266199 protein_coding
  ENST00000536871 SMG6-005 2061405-2237037 protein_coding
  ENST00000570606 SMG6-021 2186725-2266131 protein_coding
  ENST00000570659 SMG6-019 2172802-2244912 protein_coding
  ENST00000570668 SMG6-013 2186737-2240191 protein_coding
  ENST00000570756 SMG6-004 2059876-2082310 processed_transcript
  ENST00000570874 SMG6-011 2085783-2173071 retained_intron
  ENST00000571442 SMG6-015 2172797-2237391 protein_coding
  ENST00000572205 SMG6-018 2172737-2229464 protein_coding
  ENST00000572369 SMG6-008 2172668-2214349 protein_coding
  ENST00000573153 SMG6-012 2061452-2066089 processed_transcript
  ENST00000573166 SMG6-003 2059846-2088761 processed_transcript
  ENST00000573827 SMG6-023 2061551-2072003 processed_transcript
  ENST00000574501 SMG6-022 2059839-2062257 retained_intron
  ENST00000575176 SMG6-009 2172712-2212737 protein_coding
  ENST00000575338 SMG6-007 2081916-2095112 processed_transcript
  ENST00000575454 SMG6-010 2068887-2173178 protein_coding
  ENST00000575663 SMG6-014 2172804-2237580 protein_coding
  ENST00000576218 SMG6-020 2061374-2082301 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000263073ENST00000570756ENST00000574501
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000263073 18.681±4.30 12.150±0.00 8.966±3.86
ENST00000570756 N/A N/A 16.851±0.00
ENST00000574501 N/A N/A 26.756±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00093G CIL_00093G_0001 VISTA
CIL_0007RP CIL_0007RP_0001 VISTA
CIL_0007KQ CIL_0007KQ_0001 UCNEbase

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000723 IMP telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0004521 IMP endoribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005697 TAS telomerase holoenzyme complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006406 TAS mRNA export from nucleus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0035145 IDA exon-exon junction complex
GO:0035303 TAS regulation of dephosphorylation
GO:0042162 IDA telomeric DNA binding
GO:0046872 IEA metal ion binding
GO:0090502 IMP RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000038290 Smg6 protein_coding Mus_musculus

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