ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: SMG6 nonsense mediated mRNA decay factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263073 SMG6-001 ENSG00000070366 9606 - 17:2059843-2303771 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000263073
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000263073 18.681±4.30 12.150±0.00 8.966±3.86

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000184 TAS nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0000723 IMP telomere maintenance
GO:0000781 IEA chromosome, telomeric region
GO:0004521 IMP endoribonuclease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005697 TAS telomerase holoenzyme complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IDA cytosol
GO:0006406 TAS mRNA export from nucleus
GO:0010467 TAS gene expression
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0035145 IDA exon-exon junction complex
GO:0035303 TAS regulation of dephosphorylation
GO:0042162 IDA telomeric DNA binding
GO:0046872 IEA metal ion binding
GO:0090502 IMP RNA phosphodiester bond hydrolysis, endonucleolytic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000045281 Smg6-001 protein_coding Mus_musculus 0 5603
ENSMUST00000130145 Smg6-003 nonsense_mediated_decay Mus_musculus 0 2593
ENSMUST00000140197 Smg6-004 protein_coding Mus_musculus 0 1018
ENSMUST00000153226 Smg6-006 processed_transcript Mus_musculus 0 569
ENSMUST00000142038 Smg6-005 processed_transcript Mus_musculus 0 315
ENSMUST00000135522 Smg6-002 retained_intron Mus_musculus 0 200

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