ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: 2-oxoglutarate and iron-dependent oxygenase domain containing 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000087263 OGFOD1 9606 + 16:56451490-56479100 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336111 OGFOD1-002 56451524-56477129 nonsense_mediated_decay
  ENST00000561646 OGFOD1-009 56451521-56467198 protein_coding
  ENST00000562150 OGFOD1-011 56451521-56466203 protein_coding
  ENST00000563733 OGFOD1-005 56451533-56458901 retained_intron
  ENST00000565209 OGFOD1-006 56458129-56466179 processed_transcript
  ENST00000565682 OGFOD1-010 56451523-56462628 nonsense_mediated_decay
  ENST00000566157 OGFOD1-001 56451490-56479100 protein_coding
  ENST00000568172 OGFOD1-008 56451540-56466268 processed_transcript
  ENST00000568397 OGFOD1-003 56451562-56476335 protein_coding
  ENST00000569645 OGFOD1-004 56451556-56453693 retained_intron
  ENST00000569802 OGFOD1-007 56451521-56466183 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000336111ENST00000565682ENST00000566157ENST00000568172ENST00000568397
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000336111 7.571±0.00 12.559±1.89 21.670±0.00 9.260±4.94
ENST00000565682 N/A N/A N/A 27.252±13.34
ENST00000566157 N/A 4.996±0.93 7.101±0.00 3.632±1.73
ENST00000568172 N/A N/A N/A 15.125±0.00
ENST00000568397 N/A 9.776±2.03 N/A 8.576±0.83

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00048T CIL_00048T_0001 CGP
CIL_00048W CIL_00048W_0001 CGP
CIL_00048V CIL_00048V_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005506 IEA iron ion binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006449 IMP regulation of translational termination
GO:0008283 IMP cell proliferation
GO:0010494 IMP cytoplasmic stress granule
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016706 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0018126 IDA protein hydroxylation
GO:0019511 IDA peptidyl-proline hydroxylation
GO:0031418 IEA L-ascorbic acid binding
GO:0031543 IDA peptidyl-proline dioxygenase activity
GO:0031544 IDA peptidyl-proline 3-dioxygenase activity
GO:0034063 IMP stress granule assembly
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036061 ogfod1 protein_coding Danio_rerio
ENSMUSG00000033009 Ogfod1 protein_coding Mus_musculus

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