ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dehydrogenase/reductase (SDR family) member 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000100867 DHRS2 9606 + 14:23630115-23645639 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000250383 DHRS2-001 23636335-23645639 protein_coding
  ENST00000344777 DHRS2-002 23636373-23645639 protein_coding
  ENST00000432832 DHRS2-003 23630115-23644543 protein_coding
  ENST00000553600 DHRS2-009 23639339-23645295 protein_coding
  ENST00000553896 DHRS2-004 23630115-23642438 processed_transcript
  ENST00000556550 DHRS2-007 23643045-23645639 retained_intron
  ENST00000556701 DHRS2-005 23636367-23645637 retained_intron
  ENST00000556729 DHRS2-006 23638032-23645639 retained_intron
  ENST00000557535 DHRS2-008 23639293-23645639 protein_coding
  ENST00000611765 DHRS2-201 23638816-23645637 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000250383ENST00000344777ENST00000432832ENST00000553600ENST00000553896ENST00000556701ENST00000556729ENST00000557535ENST00000611765
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000250383 N/A 10.916±8.07 N/A N/A 0.039±0.02
ENST00000344777 N/A 0.572±1.12 N/A N/A 0.074±0.03
ENST00000432832 N/A N/A N/A N/A 0.066±0.02
ENST00000553600 N/A N/A N/A N/A 0.041±0.00
ENST00000553896 N/A N/A N/A N/A 0.036±0.02
ENST00000556701 N/A N/A 0.483±0.00 0.086±0.00 0.033±0.01
ENST00000556729 0.008±0.00 0.037±0.01 N/A N/A 0.018±0.02
ENST00000557535 0.124±0.00 N/A 2.420±0.00 N/A 0.088±0.06
ENST00000611765 N/A N/A N/A N/A 0.048±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00090C CIL_00090C_0001 VISTA
CIL_0009BW CIL_0009BW_0001 VISTA
CIL_0008Q4 CIL_0008Q4_0001 VISTA
CIL_0008QH CIL_0008QH_0001 VISTA
CIL_0001QP CIL_0001QP_0001 CGP
CIL_0002T7 CIL_0002T7_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004090 IDA carbonyl reductase (NADPH) activity
GO:0005634 IDA nucleus
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0008152 IEA metabolic process
GO:0008207 NAS C21-steroid hormone metabolic process
GO:0008285 NAS negative regulation of cell proliferation
GO:0009636 IDA response to toxic substance
GO:0016491 IEA oxidoreductase activity
GO:0034599 IDA cellular response to oxidative stress
GO:0043011 IEP myeloid dendritic cell differentiation
GO:0043066 IMP negative regulation of apoptotic process
GO:0055114 IEA:IDA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021135 dhrs2 protein_coding Danio_rerio
ENSMUSG00000022209 Dhrs2 protein_coding Mus_musculus

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