ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: dishevelled segment polarity protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000378891 DVL1-001 ENSG00000107404 9606 - 1:1335276-1349112 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000378891
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000378891 13.268±4.28 14.444±4.68 13.486±0.00 14.328±0.00 8.329±6.22

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001505 ISS regulation of neurotransmitter levels
GO:0001932 IEA regulation of protein phosphorylation
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0005109 IPI frizzled binding
GO:0005515 IPI:IEA protein binding
GO:0005874 IBA microtubule
GO:0005938 IBA cell cortex
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007269 ISS neurotransmitter secretion
GO:0007409 IEA axonogenesis
GO:0007411 IBA axon guidance
GO:0007528 ISS neuromuscular junction development
GO:0010976 IEA positive regulation of neuron projection development
GO:0015630 IEA microtubule cytoskeleton
GO:0016023 ISS cytoplasmic membrane-bounded vesicle
GO:0016328 IDA lateral plasma membrane
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0021915 IEP neural tube development
GO:0022007 IEA convergent extension involved in neural plate elongation
GO:0030136 IBA clathrin-coated vesicle
GO:0030177 IDA positive regulation of Wnt signaling pathway
GO:0030424 IBA axon
GO:0030425 IBA dendrite
GO:0030426 IBA growth cone
GO:0031122 IEA cytoplasmic microtubule organization
GO:0031410 IDA cytoplasmic vesicle
GO:0032091 IDA negative regulation of protein binding
GO:0032436 IMP positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034504 IMP protein localization to nucleus
GO:0035176 IEA social behavior
GO:0035372 IEA protein localization to microtubule
GO:0035556 IEA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0043025 IBA neuronal cell body
GO:0043113 ISS receptor clustering
GO:0045202 ISS synapse
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0048365 IBA Rac GTPase binding
GO:0048668 IBA collateral sprouting
GO:0048675 IBA axon extension
GO:0048813 ISS dendrite morphogenesis
GO:0050808 ISS synapse organization
GO:0060026 IBA convergent extension
GO:0060029 IEA convergent extension involved in organogenesis
GO:0060070 IDA canonical Wnt signaling pathway
GO:0060071 IDA Wnt signaling pathway, planar cell polarity pathway
GO:0060134 IEA prepulse inhibition
GO:0071340 IBA skeletal muscle acetylcholine-gated channel clustering
GO:0090103 IBA cochlea morphogenesis
GO:0090179 IBA planar cell polarity pathway involved in neural tube closure
GO:0090263 IEA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000168552 Dvl1-201 protein_coding Mus_musculus 0 1435
ENSMUST00000030948 Dvl1-001 protein_coding Mus_musculus 0 1435
ENSMUST00000141539 Dvl1-002 retained_intron Mus_musculus 0 896
ENSMUST00000143457 Dvl1-003 retained_intron Mus_musculus 0 891
ENSMUST00000133184 Dvl1-005 retained_intron Mus_musculus 0 891
ENSMUST00000156997 Dvl1-007 retained_intron Mus_musculus 0 593
ENSMUST00000171572 Dvl3-003 protein_coding Mus_musculus 0 475
ENSMUST00000003318 Dvl3-001 protein_coding Mus_musculus 0 475
ENSMUST00000171774 Dvl3-004 protein_coding Mus_musculus 0 453
ENSDART00000012450 dvl2-201 protein_coding Danio_rerio 8e-38 163

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