ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: phenazine biosynthesis-like protein domain containing
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000108187 PBLD 9606 - 10:68282660-68333049 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000277795 PBLD-003 68287027-68306879 retained_intron
  ENST00000309049 PBLD-001 68283064-68332906 protein_coding
  ENST00000336578 PBLD-002 68282660-68297134 protein_coding
  ENST00000358769 PBLD-201 68282660-68332927 protein_coding
  ENST00000468798 PBLD-006 68283064-68288963 protein_coding
  ENST00000478192 PBLD-007 68295947-68306829 retained_intron
  ENST00000495025 PBLD-004 68285081-68333049 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000277795ENST00000309049ENST00000336578ENST00000358769ENST00000468798ENST00000495025
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000277795 N/A 0.119±0.09 0.563±0.00 0.413±0.25
ENST00000309049 N/A 0.137±0.09 N/A 0.472±0.40
ENST00000336578 0.364±0.02 N/A N/A 0.431±0.06
ENST00000358769 N/A 0.439±0.28 N/A 0.805±0.41
ENST00000468798 N/A 0.583±0.21 N/A N/A
ENST00000495025 N/A 0.223±0.16 N/A 0.828±0.45

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0000H3 CIL_0000H3_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0009058 IEA biosynthetic process
GO:0010633 IMP negative regulation of epithelial cell migration
GO:0010719 IMP negative regulation of epithelial to mesenchymal transition
GO:0016853 IEA isomerase activity
GO:0030277 IMP maintenance of gastrointestinal epithelium
GO:0030512 IMP negative regulation of transforming growth factor beta receptor signaling pathway
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0060392 IGI negative regulation of SMAD protein import into nucleus
GO:0060394 IMP negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016704 PBLD (1 of 2) protein_coding Danio_rerio
ENSDARG00000026359 pbld2 protein_coding Danio_rerio
ENSMUSG00000020072 Pbld2 protein_coding Mus_musculus

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