ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020072 Pbld2 10090 + 10:63024315-63077962 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020262 Pbld2-001 63024512-63058813 protein_coding
  ENSMUST00000020266 Pbld2-201 63061582-63077962 protein_coding
  ENSMUST00000124784 Pbld2-002 63024315-63052261 protein_coding
  ENSMUST00000130531 Pbld2-003 63054210-63058128 retained_intron
  ENSMUST00000178684 Pbld2-202 63061618-63077534 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000020262ENSMUST00000020266ENSMUST00000124784ENSMUST00000130531ENSMUST00000178684
Transcript ID C166 Tie2+ EC mES
ENSMUST00000020262 0.153±0.04 0.053±0.02 0.092±0.05
ENSMUST00000020266 0.097±0.06 0.391±0.27 0.339±0.13
ENSMUST00000124784 0.353±0.17 N/A N/A
ENSMUST00000130531 0.193±0.09 0.049±0.00 0.087±0.00
ENSMUST00000178684 0.075±0.02 0.145±0.01 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0003824 IEA catalytic activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0008150 ND biological_process
GO:0009058 IEA biosynthetic process
GO:0010633 IEA negative regulation of epithelial cell migration
GO:0010719 IEA negative regulation of epithelial to mesenchymal transition
GO:0016853 IEA isomerase activity
GO:0030277 IEA maintenance of gastrointestinal epithelium
GO:0030512 IEA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0060392 IEA negative regulation of SMAD protein import into nucleus
GO:0060394 IEA negative regulation of pathway-restricted SMAD protein phosphorylation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000016704 PBLD (1 of 2) protein_coding Danio_rerio
ENSDARG00000026359 pbld2 protein_coding Danio_rerio
ENSG00000108187 PBLD phenazine biosynthesis-like protein domain containing protein_coding Homo_sapiens

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