ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: SMAD family member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000113658 SMAD5 9606 + 5:136132845-136188747 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000506223 SMAD5-008 136133823-136154002 protein_coding
  ENST00000507118 SMAD5-002 136132847-136154144 protein_coding
  ENST00000507245 SMAD5-009 136147420-136153681 retained_intron
  ENST00000507637 SMAD5-010 136160986-136172829 protein_coding
  ENST00000509297 SMAD5-004 136133353-136153763 protein_coding
  ENST00000509962 SMAD5-007 136133224-136153729 processed_transcript
  ENST00000511116 SMAD5-003 136132847-136154163 protein_coding
  ENST00000513418 SMAD5-012 136174469-136188747 nonsense_mediated_decay
  ENST00000514777 SMAD5-011 136132904-136177386 processed_transcript
  ENST00000515005 SMAD5-005 136133353-136153763 protein_coding
  ENST00000545279 SMAD5-001 136132845-136182732 protein_coding
  ENST00000545620 SMAD5-201 136132847-136182734 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000545279ENST00000545620
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000545279 N/A 5.903±3.77 0.682±0.00 6.205±0.00 5.004±3.25
ENST00000545620 1.128±0.71 2.443±0.63 3.546±0.00 4.876±0.00 2.783±1.51

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005P2 CIL_0005P2_0001 CGP
CIL_0005P3 CIL_0005P3_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001503 IEA ossification
GO:0001657 IEA ureteric bud development
GO:0001880 IEA Mullerian duct regression
GO:0002051 IEA osteoblast fate commitment
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005057 NAS receptor signaling protein activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007165 NAS signal transduction
GO:0007179 IEA transforming growth factor beta receptor signaling pathway
GO:0007281 IEA germ cell development
GO:0009880 ISS embryonic pattern specification
GO:0016021 NAS integral component of membrane
GO:0030218 IEA erythrocyte differentiation
GO:0030509 ISS BMP signaling pathway
GO:0030618 TAS transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035556 TAS intracellular signal transduction
GO:0043234 IDA protein complex
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051216 IEA cartilage development
GO:0060048 IEA cardiac muscle contraction
GO:0060348 IEA bone development
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071773 ISS cellular response to BMP stimulus
GO:1901522 ISS positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021540 Smad5 protein_coding Mus_musculus

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