ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: SMAD family member 5
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000545279 SMAD5-001 ENSG00000113658 9606 + 5:136132845-136182732 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHHSECHMVEC-DHUVECENST00000545279
Transcript ID HAoEC HHSEC HMVEC-D HUVEC
ENST00000545279 5.903±3.77 0.682±0.00 6.205±0.00 5.004±3.25

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001503 IEA ossification
GO:0001657 IEA ureteric bud development
GO:0001880 IEA Mullerian duct regression
GO:0002051 IEA osteoblast fate commitment
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005057 NAS receptor signaling protein activity
GO:0005515 IPI:IEA protein binding
GO:0005622 NAS:IEA intracellular
GO:0005634 TAS nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IEA protein phosphorylation
GO:0007165 NAS signal transduction
GO:0007179 NAS:IEA transforming growth factor beta receptor signaling pathway
GO:0007281 IEA germ cell development
GO:0009880 ISS embryonic pattern specification
GO:0016021 NAS integral component of membrane
GO:0030218 IEA erythrocyte differentiation
GO:0030509 ISS BMP signaling pathway
GO:0030618 TAS transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035556 TAS intracellular signal transduction
GO:0043234 IDA protein complex
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045893 NAS positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051216 IEA cartilage development
GO:0060048 IEA cardiac muscle contraction
GO:0060348 IEA bone development
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071773 ISS cellular response to BMP stimulus
GO:1901522 ISS positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000109874 Smad5-003 protein_coding Mus_musculus 0 2307
ENSMUST00000109876 Smad5-002 protein_coding Mus_musculus 0 2307
ENSMUST00000069557 Smad5-001 protein_coding Mus_musculus 0 2307
ENSMUST00000138677 Smad5-004 processed_transcript Mus_musculus 0 1530
ENSMUST00000132302 Smad5-005 processed_transcript Mus_musculus 0 1192
ENSMUST00000066091 Smad1-001 protein_coding Mus_musculus 0 809
ENSMUST00000109885 Smad1-002 protein_coding Mus_musculus 0 673
ENSMUST00000136702 Smad5-006 processed_transcript Mus_musculus 0 427

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