ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021540 Smad5 10090 + 13:56703010-56742377 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000069557 Smad5-001 56703010-56742377 protein_coding
  ENSMUST00000109874 Smad5-003 56703668-56740304 protein_coding
  ENSMUST00000109876 Smad5-002 56703052-56739960 protein_coding
  ENSMUST00000132302 Smad5-005 56703066-56733125 processed_transcript
  ENSMUST00000136702 Smad5-006 56733017-56738993 processed_transcript
  ENSMUST00000138677 Smad5-004 56703039-56733214 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000069557ENSMUST00000138677
Transcript ID C166 Tie2+ EC mES
ENSMUST00000069557 13.549±3.40 9.168±6.44 1.730±0.18
ENSMUST00000138677 N/A N/A 9.104±2.65

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005P2 CIL_0005P2_0002 CGP
CIL_0005P3 CIL_0005P3_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001503 IEA ossification
GO:0001525 IEA angiogenesis
GO:0001657 IEP ureteric bud development
GO:0001880 IEA Mullerian duct regression
GO:0002051 IGI osteoblast fate commitment
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007281 IMP germ cell development
GO:0009880 ISS embryonic pattern specification
GO:0030218 IMP erythrocyte differentiation
GO:0030509 TAS BMP signaling pathway
GO:0031625 IEA ubiquitin protein ligase binding
GO:0043234 ISO protein complex
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051216 IGI cartilage development
GO:0060048 IMP cardiac muscle contraction
GO:0060348 IGI bone development
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071773 IGI cellular response to BMP stimulus
GO:1901522 IGI positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000113658 SMAD5 SMAD family member 5 protein_coding Homo_sapiens

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