ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: ubiquitin specific peptidase 4 (proto-oncogene)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000114316 USP4 9606 - 3:49277831-49340712 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000265560 USP4-002 49278106-49340071 protein_coding
  ENST00000351842 USP4-001 49277831-49340033 protein_coding
  ENST00000415188 USP4-011 49316732-49340036 protein_coding
  ENST00000416417 USP4-005 49311785-49340036 protein_coding
  ENST00000431357 USP4-004 49278170-49311618 protein_coding
  ENST00000461553 USP4-009 49305778-49314044 processed_transcript
  ENST00000462673 USP4-012 49317119-49318657 processed_transcript
  ENST00000464168 USP4-013 49324697-49340053 processed_transcript
  ENST00000475873 USP4-007 49284536-49293644 processed_transcript
  ENST00000483212 USP4-006 49278143-49279231 retained_intron
  ENST00000485450 USP4-003 49278158-49312863 retained_intron
  ENST00000486549 USP4-010 49297870-49340029 processed_transcript
  ENST00000488520 USP4-008 49300595-49318774 processed_transcript
  ENST00000491791 USP4-014 49324704-49340712 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000265560ENST00000351842ENST00000431357ENST00000485450
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000265560 N/A 11.917±4.01 N/A 13.723±0.00 9.890±3.03
ENST00000351842 5.734±3.40 13.431±4.53 8.264±0.00 14.224±0.00 7.924±3.37
ENST00000431357 N/A N/A 11.641±0.00 N/A 5.045±0.00
ENST00000485450 N/A N/A N/A N/A 0.578±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000244 IMP spliceosomal tri-snRNP complex assembly
GO:0004221 IMP ubiquitin thiolesterase activity
GO:0004843 IDA:IEA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005764 TAS lysosome
GO:0005886 IDA plasma membrane
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0016579 IDA protein deubiquitination
GO:0031397 IMP negative regulation of protein ubiquitination
GO:0031647 IDA regulation of protein stability
GO:0031685 IPI adenosine receptor binding
GO:0034394 IDA protein localization to cell surface
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042802 IPI identical protein binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014770 usp4 protein_coding Danio_rerio
ENSMUSG00000032612 Usp4 protein_coding Mus_musculus

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