ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: B-cell CLL/lymphoma 11A (zinc finger protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000119866 BCL11A 9606 - 2:60451167-60553567 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000335712 BCL11A-001 60457198-60553498 protein_coding
  ENST00000356842 BCL11A-002 60451167-60553499 protein_coding
  ENST00000358510 BCL11A-006 60460274-60553431 protein_coding
  ENST00000359629 BCL11A-003 60451167-60553567 protein_coding
  ENST00000409351 BCL11A-004 60541882-60553500 processed_transcript
  ENST00000477659 BCL11A-008 60459820-60536206 processed_transcript
  ENST00000479026 BCL11A-013 60452154-60460455 processed_transcript
  ENST00000489183 BCL11A-011 60544230-60546180 processed_transcript
  ENST00000489516 BCL11A-007 60451781-60550914 processed_transcript
  ENST00000492272 BCL11A-010 60452577-60528535 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000335712ENST00000356842ENST00000358510ENST00000359629ENST00000409351ENST00000477659ENST00000479026ENST00000489183ENST00000489516ENST00000492272
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000335712 N/A 0.015±0.01 0.007±0.00 0.098±0.00 0.019±0.01
ENST00000356842 N/A 0.061±0.00 N/A N/A 0.017±0.00
ENST00000358510 N/A 0.058±0.01 N/A 0.315±0.00 0.029±0.02
ENST00000359629 N/A 0.060±0.06 N/A N/A 0.035±0.01
ENST00000409351 N/A 0.570±0.27 N/A N/A 0.113±0.07
ENST00000477659 N/A 0.111±0.00 N/A N/A 0.018±0.01
ENST00000479026 N/A 0.087±0.00 0.129±0.00 N/A 0.181±0.03
ENST00000489183 0.268±0.00 0.179±0.00 N/A N/A 0.261±0.14
ENST00000489516 N/A 0.148±0.00 N/A 0.167±0.00 0.050±0.03
ENST00000492272 0.198±0.00 N/A N/A N/A 0.095±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007LM CIL_0007LM_0001 UCNEbase
CIL_0008BH CIL_0008BH_0001 VISTA
CIL_000881 CIL_000881_0001 VISTA
CIL_0008WW CIL_0008WW_0001 VISTA
CIL_0008GM CIL_0008GM_0001 VISTA
CIL_0009DA CIL_0009DA_0001 VISTA
CIL_0008PG CIL_0008PG_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001078 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003714 IEA transcription corepressor activity
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0010629 IEA negative regulation of gene expression
GO:0010976 IDA positive regulation of neuron projection development
GO:0010977 IDA negative regulation of neuron projection development
GO:0016925 ISS protein sumoylation
GO:0030183 IEA B cell differentiation
GO:0030217 IEA T cell differentiation
GO:0030517 ISS negative regulation of axon extension
GO:0032463 IC negative regulation of protein homooligomerization
GO:0042803 TAS protein homodimerization activity
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0048671 IMP negative regulation of collateral sprouting
GO:0048672 IMP positive regulation of collateral sprouting
GO:0050773 IMP regulation of dendrite development
GO:2000171 IMP negative regulation of dendrite development
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061352 bcl11aa protein_coding Danio_rerio
ENSDARG00000063153 bcl11ab protein_coding Danio_rerio
ENSMUSG00000000861 Bcl11a protein_coding Mus_musculus

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