ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: serine/arginine-rich splicing factor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000124193 SRSF6 9606 + 20:43457928-43464247 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000244020 SRSF6-001 43457928-43464247 protein_coding
  ENST00000483871 SRSF6-002 43457928-43461334 nonsense_mediated_decay

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000244020ENST00000483871
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000244020 5.922±2.03 9.083±3.80 N/A 25.722±0.00 11.020±8.48
ENST00000483871 10.194±6.53 18.789±11.81 48.686±0.00 34.562±0.00 21.643±9.99

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0004E4 CIL_0004E4_0001 CGP
CIL_00044L CIL_00044L_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000380 IDA alternative mRNA splicing, via spliceosome
GO:0000381 IDA regulation of alternative mRNA splicing, via spliceosome
GO:0000398 TAS mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003723 IDA RNA binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006369 TAS termination of RNA polymerase II transcription
GO:0006376 IMP mRNA splice site selection
GO:0006406 TAS mRNA export from nucleus
GO:0008380 TAS RNA splicing
GO:0010467 TAS gene expression
GO:0010837 IMP regulation of keratinocyte proliferation
GO:0016607 IDA nuclear speck
GO:0031124 TAS mRNA 3'-end processing
GO:0036002 IDA pre-mRNA binding
GO:0044822 IDA poly(A) RNA binding
GO:0045617 IMP negative regulation of keratinocyte differentiation
GO:0048025 IDA negative regulation of mRNA splicing, via spliceosome
GO:0060501 IDA positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060548 IDA negative regulation of cell death
GO:0061041 IMP regulation of wound healing

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013729 srsf6a protein_coding Danio_rerio
ENSDARG00000016783 srsf6b protein_coding Danio_rerio
ENSMUSG00000016921 Srsf6 protein_coding Mus_musculus

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