ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: tripartite motif containing 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000132256 TRIM5 9606 - 11:5663557-5938619 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380027 TRIM5-003 5663563-5872358 protein_coding
  ENST00000380034 TRIM5-001 5663557-5685063 protein_coding
  ENST00000396847 TRIM5-004 5663617-5685042 protein_coding
  ENST00000412903 TRIM5-012 5678320-5938619 protein_coding
  ENST00000419850 TRIM5-013 5679962-5685043 protein_coding
  ENST00000433961 TRIM5-005 5663564-5680232 nonsense_mediated_decay
  ENST00000438025 TRIM5-009 5663831-5679807 protein_coding
  ENST00000465634 TRIM5-010 5665880-5679833 processed_transcript
  ENST00000483835 TRIM5-008 5664058-5679857 processed_transcript
  ENST00000487241 TRIM5-007 5677946-5679931 retained_intron
  ENST00000492086 TRIM5-011 5665420-5679140 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000380027ENST00000380034ENST00000396847ENST00000412903ENST00000433961ENST00000438025
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000380027 N/A N/A 1.988±0.00 N/A 1.662±0.00
ENST00000380034 2.342±0.00 8.352±4.56 N/A 18.303±0.00 18.559±10.36
ENST00000396847 1.040±0.00 0.909±0.16 N/A 3.938±0.00 3.599±1.35
ENST00000412903 N/A N/A N/A N/A 0.152±0.00
ENST00000433961 2.547±0.00 2.972±1.08 5.341±0.00 6.687±0.00 3.813±2.75
ENST00000438025 6.863±0.00 N/A N/A N/A N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000932 IDA cytoplasmic mRNA processing body
GO:0002218 IDA activation of innate immune response
GO:0002221 IDA pattern recognition receptor signaling pathway
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005794 IDA Golgi apparatus
GO:0008270 IEA zinc ion binding
GO:0008329 IDA signaling pattern recognition receptor activity
GO:0016032 IEA viral process
GO:0016874 IEA ligase activity
GO:0031664 IMP regulation of lipopolysaccharide-mediated signaling pathway
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043123 IMP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043410 IMP positive regulation of MAPK cascade
GO:0045087 IDA innate immune response
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0046872 IEA metal ion binding
GO:0051091 IMP positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051607 TAS defense response to virus
GO:0070206 IDA protein trimerization
GO:0070534 IDA protein K63-linked ubiquitination
GO:1902187 IDA negative regulation of viral release from host cell

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000030921 Trim30a protein_coding Mus_musculus
ENSMUSG00000057143 Trim12c protein_coding Mus_musculus
ENSMUSG00000057596 Trim30d protein_coding Mus_musculus
ENSMUSG00000060441 Trim5 protein_coding Mus_musculus
ENSMUSG00000066258 Trim12a protein_coding Mus_musculus
ENSMUSG00000078616 Trim30c protein_coding Mus_musculus

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