ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: sodium channel, voltage-gated, type II, alpha subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000283256 SCN2A-001 ENSG00000136531 9606 + 2:165294031-165392053 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000283256
Transcript ID HAoEC HUVEC
ENST00000283256 0.004±0.00 0.003±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001518 IEA voltage-gated sodium channel complex
GO:0005216 IEA ion channel activity
GO:0005248 ISS:IEA voltage-gated sodium channel activity
GO:0005515 IEA protein binding
GO:0005886 IBA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0030424 TAS axon
GO:0031226 ISS intrinsic component of plasma membrane
GO:0033268 ISS node of Ranvier
GO:0034706 ISS sodium channel complex
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA:ISS sodium ion transmembrane transport
GO:0042552 ISS myelination
GO:0055085 IEA transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028377 Scn2a1-001 protein_coding Mus_musculus 0 7583
ENSMUST00000100067 Scn2a1-201 protein_coding Mus_musculus 0 7581
ENSMUST00000112371 Scn1a-201 protein_coding Mus_musculus 0 5060
ENSMUST00000077489 Scn1a-004 protein_coding Mus_musculus 0 5053
ENSMUST00000094951 Scn1a-005 protein_coding Mus_musculus 0 3496
ENSMUST00000112366 Scn1a-001 protein_coding Mus_musculus 0 3494
ENSMUST00000066432 Scn3a-201 protein_coding Mus_musculus 0 3326
ENSMUST00000100069 Scn3a-001 protein_coding Mus_musculus 0 3326
ENSMUST00000169900 Scn9a-203 protein_coding Mus_musculus 0 2865
ENSMUST00000112354 Scn9a-002 protein_coding Mus_musculus 0 2865
ENSMUST00000100063 Scn9a-201 protein_coding Mus_musculus 0 2612
ENSMUST00000164384 Scn9a-202 protein_coding Mus_musculus 0 2567
ENSMUST00000100064 Scn9a-001 protein_coding Mus_musculus 0 2567
ENSDART00000090994 scn1lab-201 protein_coding Danio_rerio 0 1352
ENSDART00000151247 scn1lab-001 protein_coding Danio_rerio 0 1352
ENSMUST00000108908 Scn8a-002 protein_coding Mus_musculus 0 1195
ENSMUST00000108910 Scn8a-202 protein_coding Mus_musculus 0 1195
ENSMUST00000082209 Scn8a-201 protein_coding Mus_musculus 0 1195
ENSMUST00000156865 Scn1a-003 protein_coding Mus_musculus 0 1138
ENSMUST00000021056 Scn4a-001 protein_coding Mus_musculus 0 994
ENSMUST00000108909 Scn8a-001 protein_coding Mus_musculus 0 942
ENSMUST00000144254 Scn2a1-004 protein_coding Mus_musculus 0 640
ENSMUST00000138910 Scn1a-006 protein_coding Mus_musculus 0 536
ENSDART00000022042 scn8aa-001 protein_coding Danio_rerio 0 435
ENSMUST00000042792 Scn7a-001 protein_coding Mus_musculus 0 385
ENSMUST00000138368 Scn2a1-003 retained_intron Mus_musculus 0 366
ENSMUST00000129508 Scn1a-002 retained_intron Mus_musculus 0 309
ENSMUST00000070617 Scn11a-201 protein_coding Mus_musculus 9e-37 161

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