ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: integrin, alpha 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137809 ITGA11 9606 - 15:68296533-68432162 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000315757 ITGA11-201 68301712-68432153 protein_coding
  ENST00000423218 ITGA11-001 68296533-68432162 protein_coding
  ENST00000562826 ITGA11-009 68351256-68365522 processed_transcript
  ENST00000565868 ITGA11-008 68357079-68361641 retained_intron
  ENST00000566429 ITGA11-006 68331951-68340843 processed_transcript
  ENST00000568677 ITGA11-007 68357145-68361957 retained_intron
  ENST00000569346 ITGA11-005 68331078-68336100 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000315757ENST00000423218ENST00000562826ENST00000566429
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000315757 0.617±0.10 2.057±1.47 8.037±0.00 0.346±0.46
ENST00000423218 0.074±0.00 0.059±0.03 N/A 0.040±0.03
ENST00000562826 N/A N/A N/A 0.442±0.03
ENST00000566429 N/A N/A N/A 0.503±0.20

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00046P CIL_00046P_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IDA osteoblast differentiation
GO:0005518 IMP collagen binding
GO:0005886 TAS plasma membrane
GO:0005925 IDA focal adhesion
GO:0006929 IMP substrate-dependent cell migration
GO:0007155 TAS cell adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007229 IMP integrin-mediated signaling pathway
GO:0007517 TAS muscle organ development
GO:0008305 TAS integrin complex
GO:0016020 IDA membrane
GO:0030198 TAS extracellular matrix organization
GO:0033627 IMP cell adhesion mediated by integrin
GO:0034681 IDA integrin alpha11-beta1 complex
GO:0038064 IMP collagen receptor activity
GO:0038065 IMP collagen-activated signaling pathway
GO:0046872 IEA metal ion binding
GO:0098639 IMP collagen binding involved in cell-matrix adhesion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007950 itga11b protein_coding Danio_rerio
ENSDARG00000036086 itga11a protein_coding Danio_rerio
ENSMUSG00000032243 Itga11 protein_coding Mus_musculus

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