ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000137815 RTF1 9606 + 15:41408408-41483563 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000389629 RTF1-001 41417104-41483563 protein_coding
  ENST00000462276 RTF1-002 41417132-41452994 processed_transcript
  ENST00000473214 RTF1-003 41474587-41477249 retained_intron
  ENST00000558117 RTF1-005 41477189-41478943 retained_intron
  ENST00000558298 RTF1-004 41408408-41452942 processed_transcript
  ENST00000560447 RTF1-007 41474669-41477578 protein_coding
  ENST00000561076 RTF1-006 41478485-41480290 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000389629
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000389629 4.088±0.93 13.976±6.94 9.263±0.00 12.211±0.00 8.316±4.64

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0005FB CIL_0005FB_0001 CGP
CIL_0005FC CIL_0005FC_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 ISS negative regulation of transcription from RNA polymerase II promoter
GO:0001711 ISS endodermal cell fate commitment
GO:0003677 IEA DNA binding
GO:0003697 IDA single-stranded DNA binding
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0006352 IEA DNA-templated transcription, initiation
GO:0016055 IEA Wnt signaling pathway
GO:0016570 IEA histone modification
GO:0016593 IDA Cdc73/Paf1 complex
GO:0019827 IDA stem cell maintenance
GO:0032968 IDA positive regulation of transcription elongation from RNA polymerase II promoter
GO:0044822 IDA poly(A) RNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051571 IEA positive regulation of histone H3-K4 methylation
GO:0080182 IEA histone H3-K4 trimethylation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008947 rtf1 protein_coding Danio_rerio
ENSMUSG00000027304 Rtf1 protein_coding Mus_musculus

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