ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: corepressor interacting with RBPJ, 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138433 CIR1 9606 - 2:174348022-174395715 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000342016 CIR1-001 174348022-174395715 protein_coding
  ENST00000377973 CIR1-007 174358173-174380680 protein_coding
  ENST00000461454 CIR1-005 174378687-174395706 retained_intron
  ENST00000464393 CIR1-006 174349135-174351963 retained_intron
  ENST00000472169 CIR1-004 174387263-174395709 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000342016ENST00000377973ENST00000461454ENST00000464393ENST00000472169
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000342016 3.207±0.00 3.588±2.00 4.917±0.00 8.593±0.00 6.037±3.58
ENST00000377973 5.539±1.29 N/A N/A N/A 1.670±0.00
ENST00000461454 N/A 2.170±0.27 N/A N/A 0.742±0.31
ENST00000464393 N/A N/A N/A N/A 2.272±0.00
ENST00000472169 N/A N/A N/A N/A 1.169±0.16

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0007OE CIL_0007OE_0001 UCNEbase
CIL_0008JW CIL_0008JW_0001 VISTA
CIL_0008K1 CIL_0008K1_0001 VISTA
CIL_0008S8 CIL_0008S8_0001 VISTA
CIL_00096H CIL_00096H_0001 VISTA
CIL_0008GI CIL_0008GI_0001 VISTA
CIL_0008K2 CIL_0008K2_0001 VISTA
CIL_0001HA CIL_0001HA_0001 CGP
CIL_0003IH CIL_0003IH_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000118 IDA histone deacetylase complex
GO:0003676 IEA nucleic acid binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003705 TAS RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0003714 TAS transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006397 IEA mRNA processing
GO:0008270 IEA zinc ion binding
GO:0008380 IEA RNA splicing
GO:0045892 IDA negative regulation of transcription, DNA-templated

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000041777 Cir1 protein_coding Mus_musculus

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