ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: RasGEF domain family, member 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000138670 RASGEF1B 9606 - 4:81426393-82044244 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000264400 RASGEF1B-001 81427065-81471915 protein_coding
  ENST00000335927 RASGEF1B-005 81427449-81471904 protein_coding
  ENST00000436139 RASGEF1B-003 81450893-81471890 protein_coding
  ENST00000504863 RASGEF1B-006 81434676-81471907 protein_coding
  ENST00000507538 RASGEF1B-004 81458983-81471928 retained_intron
  ENST00000509081 RASGEF1B-002 81426393-81471236 protein_coding
  ENST00000512716 RASGEF1B-008 81459479-82044244 protein_coding
  ENST00000514889 RASGEF1B-007 81452029-81457602 processed_transcript
  ENST00000613784 RASGEF1B-201 81450894-81471890 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000264400ENST00000335927ENST00000436139ENST00000504863ENST00000507538ENST00000509081ENST00000514889ENST00000613784
Transcript ID BECs HAoEC HUVEC
ENST00000264400 N/A 0.068±0.02 0.014±0.00
ENST00000335927 N/A 0.090±0.00 0.066±0.01
ENST00000436139 0.027±0.00 0.017±0.01 0.015±0.01
ENST00000504863 N/A 0.122±0.06 0.060±0.03
ENST00000507538 N/A 0.073±0.00 0.088±0.00
ENST00000509081 0.016±0.00 0.080±0.09 0.023±0.01
ENST00000514889 0.177±0.00 0.230±0.11 0.139±0.13
ENST00000613784 N/A 0.025±0.01 0.008±0.00

Conserved Regions

Region IDSub-RegionRegion Type
CIL_000086 CIL_000086_0002 CGP
CIL_0008G8 CIL_0008G8_0001 VISTA

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005088 IDA Ras guanyl-nucleotide exchange factor activity
GO:0005622 IEA intracellular
GO:0005768 IEA endosome
GO:0007264 IEA small GTPase mediated signal transduction
GO:0032320 IDA positive regulation of Ras GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033614 rasgef1ba protein_coding Danio_rerio
ENSDARG00000044251 rasgef1bb protein_coding Danio_rerio
ENSMUSG00000029333 Rasgef1b protein_coding Mus_musculus

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