ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: dehydrogenase/reductase (SDR family) member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000157326 DHRS4 9606 + 14:23953586-23969279 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000313250 DHRS4-002 23953586-23969274 protein_coding
  ENST00000397074 DHRS4-001 23953786-23969176 protein_coding
  ENST00000397075 DHRS4-003 23953779-23969009 protein_coding
  ENST00000543741 DHRS4-004 23953770-23968123 protein_coding
  ENST00000558263 DHRS4-005 23953734-23969274 protein_coding
  ENST00000558581 DHRS4-007 23953789-23969279 protein_coding
  ENST00000559632 DHRS4-006 23953789-23969274 protein_coding
  ENST00000559975 DHRS4-008 23966358-23969274 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000313250ENST00000397075ENST00000543741
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000313250 N/A 4.017±1.61 3.507±0.00 4.127±2.32
ENST00000397075 18.058±1.65 7.535±3.64 11.241±0.00 12.524±3.57
ENST00000543741 N/A N/A N/A 0.534±0.35

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002T7 CIL_0002T7_0001 CGP

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000253 IDA 3-keto sterol reductase activity
GO:0004090 IDA carbonyl reductase (NADPH) activity
GO:0005102 IPI receptor binding
GO:0005634 IDA nucleus
GO:0005739 ISS mitochondrion
GO:0005777 IDA peroxisome
GO:0005778 IDA peroxisomal membrane
GO:0006066 IDA alcohol metabolic process
GO:0008152 IEA metabolic process
GO:0008202 IDA steroid metabolic process
GO:0016491 IEA oxidoreductase activity
GO:0016655 IDA oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0018455 IDA alcohol dehydrogenase [NAD(P)+] activity
GO:0031965 IDA nuclear membrane
GO:0042180 IDA cellular ketone metabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0051262 IDA protein tetramerization
GO:0055114 IEA:TAS oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021135 dhrs2 protein_coding Danio_rerio
ENSMUSG00000022210 Dhrs4 protein_coding Mus_musculus

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