ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: runt-related transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000159216 RUNX1 9606 - 21:34787801-36004667 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300305 RUNX1-002 34787801-35049344 protein_coding
  ENST00000344691 RUNX1-001 34787801-34888690 protein_coding
  ENST00000358356 RUNX1-005 34821279-34888690 protein_coding
  ENST00000399237 RUNX1-012 34834410-34889790 protein_coding
  ENST00000399240 RUNX1-009 34791786-34887183 protein_coding
  ENST00000416754 RUNX1-004 34892925-35049270 protein_coding
  ENST00000437180 RUNX1-201 34787801-35049298 protein_coding
  ENST00000455571 RUNX1-010 34880606-35049298 protein_coding
  ENST00000460207 RUNX1-017 35954660-35984749 processed_transcript
  ENST00000467577 RUNX1-008 34856289-34859578 processed_transcript
  ENST00000467692 RUNX1-016 35372507-35580760 processed_transcript
  ENST00000468726 RUNX1-014 35064716-35065072 processed_transcript
  ENST00000469087 RUNX1-007 34832961-34856447 retained_intron
  ENST00000475045 RUNX1-013 34887046-36004667 protein_coding
  ENST00000479325 RUNX1-006 34821279-34829970 processed_transcript
  ENST00000482318 RUNX1-003 34791755-35049288 nonsense_mediated_decay
  ENST00000494829 RUNX1-015 35435661-35465329 processed_transcript

Homo sapiens Ensembl GRCh38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000344691ENST00000358356ENST00000399240ENST00000482318
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000344691 N/A 2.567±1.09 0.339±0.00 2.439±0.00 1.994±1.49
ENST00000358356 0.986±0.00 1.090±0.16 N/A N/A 1.695±0.90
ENST00000399240 4.321±1.65 N/A N/A N/A 2.173±1.50
ENST00000482318 N/A N/A 0.722±0.00 N/A 1.011±0.43

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008ZS CIL_0008ZS_0001 VISTA
CIL_00094R CIL_00094R_0001 VISTA
CIL_00078F CIL_00078F_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000975 IDA regulatory region DNA binding
GO:0001501 IEA skeletal system development
GO:0001701 IEA in utero embryonic development
GO:0001889 IEA liver development
GO:0002318 IEA myeloid progenitor cell differentiation
GO:0003677 IDA:IEA DNA binding
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005509 IDA calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005604 IEA basement membrane
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007417 IEA central nervous system development
GO:0008134 IDA transcription factor binding
GO:0009966 IEA regulation of signal transduction
GO:0030097 TAS hemopoiesis
GO:0030099 IDA myeloid cell differentiation
GO:0030182 IEA neuron differentiation
GO:0030853 IMP negative regulation of granulocyte differentiation
GO:0030854 IMP positive regulation of granulocyte differentiation
GO:0031069 IEA hair follicle morphogenesis
GO:0035162 IEA embryonic hemopoiesis
GO:0042803 IDA protein homodimerization activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IDA protein heterodimerization activity
GO:0048266 IEA behavioral response to pain
GO:0048666 IEA neuron development
GO:0048935 TAS peripheral nervous system neuron development
GO:0060216 IEA definitive hemopoiesis
GO:0070491 IEA repressing transcription factor binding
GO:0071336 IEA regulation of hair follicle cell proliferation
GO:0071425 TAS hematopoietic stem cell proliferation
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:2000872 IEA positive regulation of progesterone secretion

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087646 RUNX1 (1 of 2) protein_coding Danio_rerio
ENSMUSG00000022952 Runx1 protein_coding Mus_musculus

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