ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: PBX/knotted 1 homeobox 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000160199 PKNOX1 9606 + 21:42974510-43033931 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000291547 PKNOX1-001 42974510-43033582 protein_coding
  ENST00000418336 PKNOX1-006 42974535-43007712 retained_intron
  ENST00000432907 PKNOX1-201 42974510-43033931 protein_coding
  ENST00000456957 PKNOX1-007 43003889-43007515 retained_intron
  ENST00000474336 PKNOX1-003 43021151-43028781 retained_intron
  ENST00000480179 PKNOX1-002 42974662-43018051 retained_intron
  ENST00000557820 PKNOX1-008 43020451-43029949 processed_transcript
  ENST00000558955 PKNOX1-009 43024817-43030214 retained_intron
  ENST00000560448 PKNOX1-005 43004322-43030331 nonsense_mediated_decay
  ENST00000607049 PKNOX1-011 43018131-43030162 retained_intron
  ENST00000607150 PKNOX1-010 43024435-43028875 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000291547ENST00000418336ENST00000432907ENST00000558955ENST00000560448ENST00000607049
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000291547 1.193±0.52 2.332±0.57 0.679±0.00 4.141±0.00 2.712±1.12
ENST00000418336 N/A N/A N/A N/A 6.083±2.42
ENST00000432907 1.066±0.21 N/A N/A N/A 0.208±0.08
ENST00000558955 9.862±2.84 N/A N/A N/A N/A
ENST00000560448 N/A 2.806±0.76 1.838±0.00 N/A 2.534±1.27
ENST00000607049 4.961±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00013D CIL_00013D_0002 CGP
CIL_0000D3 CIL_0000D3_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0003677 IEA DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003705 IEA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0030097 IEA hemopoiesis
GO:0030217 IEA T cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0043010 IEA camera-type eye development
GO:0043565 IEA sequence-specific DNA binding
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018765 pknox1.1 protein_coding Danio_rerio
ENSDARG00000036542 pknox1.2 protein_coding Danio_rerio
ENSMUSG00000006705 Pknox1 protein_coding Mus_musculus

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