ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: glutamate receptor, metabotropic 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000164082 GRM2 9606 + 3:51707070-51718613 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000296479 GRM2-002 51707088-51718112 nonsense_mediated_decay
  ENST00000395052 GRM2-001 51707070-51718410 protein_coding
  ENST00000419928 GRM2-007 51707411-51709193 protein_coding
  ENST00000442933 GRM2-005 51708845-51718252 protein_coding
  ENST00000464585 GRM2-004 51707305-51718613 retained_intron
  ENST00000475478 GRM2-003 51707090-51718613 processed_transcript
  ENST00000477330 GRM2-008 51711272-51712581 processed_transcript
  ENST00000496661 GRM2-006 51711272-51714068 processed_transcript

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000296479ENST00000395052ENST00000419928ENST00000442933ENST00000464585ENST00000475478ENST00000496661
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000296479 N/A 0.059±0.00 N/A 0.010±0.00
ENST00000395052 N/A 0.088±0.03 N/A 0.033±0.02
ENST00000419928 N/A N/A N/A 0.112±0.00
ENST00000442933 N/A 0.082±0.02 N/A 0.042±0.03
ENST00000464585 0.011±0.00 0.047±0.03 0.022±0.00 0.018±0.01
ENST00000475478 N/A 0.082±0.05 0.126±0.00 0.064±0.04
ENST00000496661 0.319±0.00 N/A N/A 0.030±0.01

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003FF CIL_0003FF_0002 CGP
CIL_00087C CIL_00087C_0001 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001641 IBA group II metabotropic glutamate receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0005246 IBA calcium channel regulator activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005886 TAS plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007194 TAS negative regulation of adenylate cyclase activity
GO:0007196 IBA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0008066 TAS glutamate receptor activity
GO:0014047 IEA glutamate secretion
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0030424 IEA axon
GO:0042734 IBA presynaptic membrane
GO:0043005 IEA neuron projection
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004150 grm2a protein_coding Danio_rerio
ENSDARG00000007195 GRM2 (2 of 2) protein_coding Danio_rerio
ENSMUSG00000023192 Grm2 protein_coding Mus_musculus

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