ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: signal transducer and activator of transcription 6, interleukin-4 induced
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166888 STAT6 9606 - 12:57095408-57132139 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300134 STAT6-001 57095408-57111433 protein_coding
  ENST00000454075 STAT6-004 57096365-57111374 protein_coding
  ENST00000537215 STAT6-006 57096345-57111359 protein_coding
  ENST00000538913 STAT6-008 57096200-57111346 protein_coding
  ENST00000543873 STAT6-003 57096248-57110306 protein_coding
  ENST00000553275 STAT6-018 57107666-57111413 protein_coding
  ENST00000553397 STAT6-020 57106737-57111192 protein_coding
  ENST00000553499 STAT6-010 57106708-57132139 protein_coding
  ENST00000553533 STAT6-014 57099798-57105252 protein_coding
  ENST00000554202 STAT6-012 57098745-57099104 retained_intron
  ENST00000554663 STAT6-023 57107256-57110306 protein_coding
  ENST00000554764 STAT6-007 57096446-57111353 nonsense_mediated_decay
  ENST00000554825 STAT6-019 57107261-57111374 protein_coding
  ENST00000555104 STAT6-017 57106750-57110289 nonsense_mediated_decay
  ENST00000555222 STAT6-005 57095904-57102447 retained_intron
  ENST00000555318 STAT6-013 57097105-57099794 protein_coding
  ENST00000555375 STAT6-015 57099419-57102990 protein_coding
  ENST00000555641 STAT6-025 57104468-57108283 retained_intron
  ENST00000555849 STAT6-021 57106693-57110543 protein_coding
  ENST00000556155 STAT6-002 57096341-57129100 protein_coding
  ENST00000556259 STAT6-024 57106693-57111231 protein_coding
  ENST00000557563 STAT6-011 57096243-57097290 retained_intron
  ENST00000557635 STAT6-022 57107637-57110340 protein_coding
  ENST00000557781 STAT6-016 57103273-57105317 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000300134ENST00000454075ENST00000554825ENST00000555222
Transcript ID BECs HAoEC HUVEC
ENST00000300134 7.590±0.28 18.384±13.52 27.863±17.38
ENST00000454075 N/A N/A 0.276±0.00
ENST00000554825 N/A N/A 89.272±8.10
ENST00000555222 N/A N/A 12.072±10.06

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0002296 IEA T-helper 1 cell lineage commitment
GO:0002829 IEA negative regulation of type 2 immune response
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS:IEA signal transduction
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019903 IPI protein phosphatase binding
GO:0032481 TAS positive regulation of type I interferon production
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0034097 IEA response to cytokine
GO:0035771 IMP interleukin-4-mediated signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0042802 IPI identical protein binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045121 IEA membrane raft
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048295 IEA positive regulation of isotype switching to IgE isotypes
GO:0060443 IEA mammary gland morphogenesis
GO:0070301 IEA cellular response to hydrogen peroxide
GO:1902170 IEA cellular response to reactive nitrogen species

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000015902 stat6 protein_coding Danio_rerio
ENSMUSG00000002147 Stat6 protein_coding Mus_musculus

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