ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: signal transducer and activator of transcription 6, interleukin-4 induced
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000300134 STAT6-001 ENSG00000166888 9606 - 12:57095408-57111433 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000300134
Transcript ID BECs HAoEC HUVEC
ENST00000300134 7.590±0.28 18.384±13.52 27.863±17.38

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0000790 IEA nuclear chromatin
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0002296 IEA T-helper 1 cell lineage commitment
GO:0002829 IEA negative regulation of type 2 immune response
GO:0003677 IEA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS:IEA signal transduction
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0019903 IPI protein phosphatase binding
GO:0032481 TAS positive regulation of type I interferon production
GO:0033598 IEA mammary gland epithelial cell proliferation
GO:0034097 IEA response to cytokine
GO:0035771 IMP interleukin-4-mediated signaling pathway
GO:0042127 IEA regulation of cell proliferation
GO:0042802 IPI identical protein binding
GO:0043565 IEA sequence-specific DNA binding
GO:0045087 TAS innate immune response
GO:0045121 IEA membrane raft
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048295 IEA positive regulation of isotype switching to IgE isotypes
GO:0060443 IEA mammary gland morphogenesis
GO:0070301 IEA cellular response to hydrogen peroxide
GO:1902170 IEA cellular response to reactive nitrogen species

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000092074 Stat6-001 protein_coding Mus_musculus 0 2715
ENSMUST00000156231 Stat6-004 retained_intron Mus_musculus 0 520
ENSMUST00000120279 Stat6-002 protein_coding Mus_musculus 0 372
ENSMUST00000145470 Stat6-005 retained_intron Mus_musculus 0 206
ENSMUST00000026469 Nab2-001 protein_coding Mus_musculus 4e-27 128
ENSMUST00000099157 Nab2-002 protein_coding Mus_musculus 2e-26 126

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