ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168758 SEMA4C 9606 - 2:96859716-96870757 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305476 SEMA4C-001 96859716-96869971 protein_coding
  ENST00000442264 SEMA4C-006 96865234-96868588 protein_coding
  ENST00000449330 SEMA4C-005 96865667-96870757 protein_coding
  ENST00000467747 SEMA4C-003 96859748-96863328 retained_intron
  ENST00000474420 SEMA4C-004 96859736-96862447 retained_intron
  ENST00000482925 SEMA4C-002 96859742-96866930 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000305476ENST00000467747ENST00000474420ENST00000482925
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000305476 1.017±0.56 1.744±0.91 25.004±0.00 2.619±0.00 4.000±2.76
ENST00000467747 1.098±0.00 0.258±0.00 N/A N/A 1.044±0.57
ENST00000474420 1.013±0.00 N/A 34.514±0.00 N/A N/A
ENST00000482925 N/A 0.514±0.24 N/A 1.853±0.00 0.545±0.57

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0002UD CIL_0002UD_0001 CGP
CIL_0002UE CIL_0002UE_0001 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 ISS neural tube closure
GO:0004872 IEA receptor activity
GO:0005515 IEA protein binding
GO:0005615 IDA extracellular space
GO:0007275 IEA multicellular organismal development
GO:0014069 ISS postsynaptic density
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0021535 ISS cell migration in hindbrain
GO:0021549 IEA cerebellum development
GO:0030054 IEA cell junction
GO:0030672 ISS synaptic vesicle membrane
GO:0032874 IDA positive regulation of stress-activated MAPK cascade
GO:0042692 IDA muscle cell differentiation
GO:0045211 IEA postsynaptic membrane
GO:0071526 ISS semaphorin-plexin signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079611 sema4c protein_coding Danio_rerio
ENSMUSG00000026121 Sema4c protein_coding Mus_musculus

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