ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000306897 RAC3-001 ENSG00000169750 9606 + 17:82031624-82034202 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000306897
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000306897 23.315±4.25 9.261±4.23 4.355±0.00 13.277±14.04

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003924 IDA GTPase activity
GO:0005515 IPI protein binding
GO:0005525 IEA GTP binding
GO:0005622 IEA intracellular
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0006184 IDA:IEA GTP catabolic process
GO:0007165 IEA signal transduction
GO:0007264 IEA:TAS small GTPase mediated signal transduction
GO:0012505 IDA endomembrane system
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0030031 IDA cell projection assembly
GO:0030036 IDA actin cytoskeleton organization
GO:0030426 IDA growth cone
GO:0031175 IEA neuron projection development
GO:0031941 IDA filamentous actin
GO:0033630 IDA positive regulation of cell adhesion mediated by integrin
GO:0035556 TAS intracellular signal transduction
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0048306 IPI calcium-dependent protein binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050885 IEA neuromuscular process controlling balance
GO:0050905 IEA neuromuscular process
GO:0051056 TAS regulation of small GTPase mediated signal transduction
GO:0070062 IDA extracellular vesicular exosome
GO:0071944 IDA cell periphery
GO:1900026 IDA positive regulation of substrate adhesion-dependent cell spreading

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018156 Rac3-001 protein_coding Mus_musculus 0 1182
ENSMUST00000142229 Rac3-002 protein_coding Mus_musculus 0 676
ENSMUST00000134322 Rac3-003 processed_transcript Mus_musculus 0 640

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