ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description: IMP (inosine 5'-monophosphate) dehydrogenase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178035 IMPDH2 9606 - 3:49024325-49029408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000326739 IMPDH2-001 49024325-49029390 protein_coding
  ENST00000429182 IMPDH2-006 49024325-49028473 protein_coding
  ENST00000442157 IMPDH2-010 49026517-49029378 protein_coding
  ENST00000462980 IMPDH2-008 49026324-49028142 retained_intron
  ENST00000463903 IMPDH2-005 49024329-49024838 retained_intron
  ENST00000466147 IMPDH2-002 49024325-49025193 retained_intron
  ENST00000472328 IMPDH2-004 49024325-49024976 retained_intron
  ENST00000481274 IMPDH2-007 49024491-49025415 retained_intron
  ENST00000484872 IMPDH2-003 49024343-49025243 retained_intron
  ENST00000485500 IMPDH2-011 49027711-49029398 retained_intron
  ENST00000491610 IMPDH2-009 49026545-49028127 retained_intron
  ENST00000496837 IMPDH2-012 49027870-49029408 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000326739ENST00000462980ENST00000472328ENST00000484872ENST00000496837
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000326739 80.609±23.83 155.955±53.10 11.550±0.00 73.318±0.00 64.285±37.45
ENST00000462980 N/A N/A N/A N/A 26.143±0.00
ENST00000472328 151.567±0.00 N/A 44.731±0.00 N/A N/A
ENST00000484872 183.053±7.66 N/A 32.561±0.00 N/A N/A
ENST00000496837 N/A N/A N/A N/A 18.868±14.45

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IDA nucleotide binding
GO:0003677 IEA DNA binding
GO:0003723 IEA RNA binding
GO:0003824 IEA catalytic activity
GO:0003938 IEA IMP dehydrogenase activity
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005778 IDA peroxisomal membrane
GO:0005829 TAS cytosol
GO:0006051 IEA N-acetylmannosamine metabolic process
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006177 IEA GMP biosynthetic process
GO:0009168 TAS purine ribonucleoside monophosphate biosynthetic process
GO:0016020 IDA membrane
GO:0016491 IEA oxidoreductase activity
GO:0018580 IEA nitronate monooxygenase activity
GO:0030554 IEA adenyl nucleotide binding
GO:0044281 TAS small molecule metabolic process
GO:0046651 IEA lymphocyte proliferation
GO:0046872 IEA metal ion binding
GO:0047465 IEA N-acylglucosamine-6-phosphate 2-epimerase activity
GO:0051289 IEA protein homotetramerization
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0060041 IEA retina development in camera-type eye
GO:0070062 IDA extracellular vesicular exosome
GO:0071353 IEA cellular response to interleukin-4

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000062867 Impdh2 protein_coding Mus_musculus

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