ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: EPH receptor B4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000358173 EPHB4-001 ENSG00000196411 9606 - 7:100802565-100827499 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000358173
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000358173 17.102±1.17 23.086±8.84 58.872±0.00 41.650±30.28

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 ISS angiogenesis
GO:0002042 IDA cell migration involved in sprouting angiogenesis
GO:0003007 ISS heart morphogenesis
GO:0004672 IEA protein kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0004714 IDA transmembrane receptor protein tyrosine kinase activity
GO:0005003 IDA:IEA ephrin receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 IDA:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007155 IDA cell adhesion
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0046777 IDA protein autophosphorylation
GO:0048013 IDA:IEA ephrin receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000144296 Ephb4-004 nonsense_mediated_decay Mus_musculus 0 3482
ENSMUST00000061244 Ephb4-001 protein_coding Mus_musculus 0 3482
ENSMUST00000111055 Ephb4-002 protein_coding Mus_musculus 0 3349
ENSMUST00000166239 Ephb4-201 protein_coding Mus_musculus 0 3315
ENSMUST00000111054 Ephb4-003 protein_coding Mus_musculus 0 3013
ENSMUST00000035129 Ephb1-001 protein_coding Mus_musculus 0 686
ENSMUST00000085169 Ephb1-003 protein_coding Mus_musculus 0 604
ENSMUST00000006614 Epha2-001 protein_coding Mus_musculus 0 364

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