ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000002688 Prkd1 10090 - 12:50341231-50649223 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000002765 Prkd1-201 50341231-50649223 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Sequences
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000002765
Transcript ID C166 Tie2+ EC mES
ENSMUST00000002765 4.213±0.46 1.047±0.50 1.946±1.14

Conserved Regions

Region IDSub-RegionRegion Type
CIL_00099Q CIL_00099Q_0002 VISTA
CIL_0008M6 CIL_0008M6_0002 VISTA
CIL_00094H CIL_00094H_0002 VISTA
CIL_0008VR CIL_0008VR_0002 VISTA
CIL_00092M CIL_00092M_0002 VISTA
CIL_00095N CIL_00095N_0002 VISTA
CIL_0008C7 CIL_0008C7_0002 VISTA
CIL_0005EN CIL_0005EN_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004697 IEA protein kinase C activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005802 IDA trans-Golgi network
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005938 IDA cell cortex
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0007030 ISS Golgi organization
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0010837 IMP regulation of keratinocyte proliferation
GO:0010976 ISS positive regulation of neuron projection development
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0032793 IEA positive regulation of CREB transcription factor activity
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0034599 ISS cellular response to oxidative stress
GO:0035924 ISS cellular response to vascular endothelial growth factor stimulus
GO:0038033 IEA positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0042802 IEA identical protein binding
GO:0043123 ISS positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045087 IEA innate immune response
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0045766 ISS positive regulation of angiogenesis
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway
GO:0048193 IMP Golgi vesicle transport
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0060548 ISS negative regulation of cell death
GO:1901727 IEA positive regulation of histone deacetylase activity
GO:2001028 IEA positive regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075949 prkd1 protein_coding Danio_rerio
ENSG00000184304 PRKD1 protein kinase D1 protein_coding Homo_sapiens

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