ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000069557 Smad5-001 ENSMUSG00000021540 10090 + 13:56703010-56742377 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000069557
Transcript ID C166 Tie2+ EC mES
ENSMUST00000069557 13.549±3.40 9.168±6.44 1.730±0.18

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001503 IEA ossification
GO:0001525 IEA angiogenesis
GO:0001657 IEP ureteric bud development
GO:0001880 IEA Mullerian duct regression
GO:0002051 IGI osteoblast fate commitment
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0007281 IMP germ cell development
GO:0009880 ISS embryonic pattern specification
GO:0030218 IMP erythrocyte differentiation
GO:0030509 TAS BMP signaling pathway
GO:0031625 IEA ubiquitin protein ligase binding
GO:0043234 ISO protein complex
GO:0045669 IGI positive regulation of osteoblast differentiation
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0051216 IGI cartilage development
GO:0060048 IMP cardiac muscle contraction
GO:0060348 IGI bone development
GO:0071407 IDA cellular response to organic cyclic compound
GO:0071773 IGI cellular response to BMP stimulus
GO:1901522 IGI positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000506223 SMAD5-008 protein_coding Homo_sapiens 0 411
ENST00000507118 SMAD5-002 protein_coding Homo_sapiens 0 717
ENST00000507637 SMAD5-010 protein_coding Homo_sapiens 0 667
ENST00000511116 SMAD5-003 protein_coding Homo_sapiens 0 652
ENST00000513418 SMAD5-012 nonsense_mediated_decay Homo_sapiens 0 231
ENST00000514777 SMAD5-011 processed_transcript Homo_sapiens 0 717
ENST00000545279 SMAD5-001 protein_coding Homo_sapiens 0 2307
ENST00000545620 SMAD5-201 protein_coding Homo_sapiens 0 2409

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